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Year in Review: North Carolina’s 24 in 2024The human immunodeficiency virus (HIV) is well-known for its impact on the immune system and its effects on other systems in the body. One area that is particularly vulnerable in people with HIV is the skin. Skin issues are often one of the first visible signs of HIV infection and according to Sunway Medical Centre, Sunway City’s consultant dermatologist Dr Sharifah Rosniza Syed Nong Chek, an estimated 90% of individuals with HIV experience skin-related symptoms at some point. Understanding the types of skin conditions associated with HIV, their symptoms and how to manage them can make a significant difference in maintaining health and quality of life for people living with HIV. Why HIV affects the skin HIV weakens the immune system, making it more difficult for the body to defend itself against infections, including those affecting the skin, says Dr Sharifah Rosniza. While modern antiretroviral therapies (ART) have greatly improved the management of HIV, some skin conditions still pose challenges and can cause discomfort, pain, or, in some cases, serious health risks. Skin manifestations of HIV infection can appear as early as three weeks after HIV infection. “The patient can experience what we call an acute HIV rash. “This rash is associated with other symptoms such as fever, sore throat, enlarged lymph nodes, maybe even nausea, vomiting and diarrhoea. The rash is generalised and lasts for about two weeks before it goes away,” she says. There is also a latent period (incubation period) that can last for a while. Once the HIV infection has established itself, other types of skin disorders can then manifest and Dr Sharifah Rosniza says that these can be broadly divided into three types: Dr Sharifah Rosniza emphasises the importance of consistency with antiretroviral therapy (ART) to help reduce the incidence of skin complications. Common skin disorders There are several skin disorders related to HIV that vary in appearance and severity depending on the stage of HIV infection and the level of immune suppression. Some of the more common skin disorders related to HIV include: 1. Seborrheic dermatitis Symptoms: Red, itchy and flaky patches, often on the scalp, face, eyebrows, or chest. Cause and treatment: Seborrheic dermatitis is common and more severe in people with HIV and it can be caused partly by immunosuppression and an overgrowth of a natural skin yeast, Malassezia. Topical antifungals and topical corticosteroids are often effective and maintaining a proper skincare routine can help manage flare-ups. 2. Psoriasis Symptoms: Scaly, red plaques, particularly on the outer elbows, knees, scalp and lower back. Cause and treatment: Psoriasis may appear or worsen in individuals with HIV. Treatments include topical corticosteroids, tar-based therapies and other medications to reduce inflammation and control symptoms. 3. Molluscum contagiosum Symptoms: Small, raised, pearly bumps on the skin. Cause and treatment: Molluscum contagiosum is a viral skin infection that’s more common in those with HIV due to their lowered immunity. It can be treated with cryotherapy and will usually improve with the commencement of ART. 4. Fungal infections (e.g. candidiasis and tinea) Symptoms: Itchy, red and sometimes scaly patches; in the case of oral thrush, white patches inside the mouth. Cause and treatment: Fungal infections are particularly common in those with weakened immune systems. Antifungal medications, both topical and oral, are the primary treatment. By raising awareness on skin conditions, we can foster a more understanding and supportive environment for those living with HIV. - UNSPLASH Managing HIV-related skin conditions Dr Sharifah Rosniza emphasises the importance of consistency with ART as it has essentially transformed HIV into a manageable chronic condition, significantly reducing the incidence of skin complications. By keeping the immune system functioning better, ART reduces the likelihood of opportunistic skin infections and other skin conditions. Proper skincare and hygiene are important. Simple habits, like gentle cleansing, moisturising and avoiding harsh or irritating products, can go a long way in managing and preventing flare-ups. Sun protection is also a very important routine to prevent skin complications and reduce risk of skin cancers. Because skin conditions are often the first visible sign of HIV progression, it’s essential for individuals with HIV to monitor their skin health closely. Routine skin checks, either self-examinations or by a healthcare provider, can lead to early detection of potentially serious conditions. Additionally, regular communication with healthcare providers allows for timely adjustments to HIV treatment plans if side effects or immune responses impact skin health. Raising awareness and reducing stigma Living with HIV presents many challenges, but skin issues shouldn’t be ignored or underestimated. Dr Sharifah Rosniza emphasises that with advancements in HIV treatment and a proactive approach to managing skin health, individuals with HIV can achieve a high quality of life. World AIDS Day is not only a time to educate people about HIV and its symptoms but also to combat stigma. Skin conditions can be highly visible, making people living with HIV more vulnerable to social stigma and discrimination. By raising awareness and providing accurate information, we can foster a more understanding and supportive environment, encouraging people to seek help without fear of judgement.bookmaker 1xbet logo hd



Acentra Health Campaign Raises $31,000 to Help Southeastern U.S. Communities Recover from Hurricane DevastationHaid added six rebounds and four steals for the Blue Devils (8-4). Max Frazier scored 17 points and added nine rebounds. Davonte Sweatman had 14 points and shot 5 for 9 (1 for 3 from 3-point range) and 3 of 4 from the free-throw line. The Bobcats (5-7) were led by Amarri Tice, who posted 21 points, 10 rebounds and four steals. Paul Otieno added 13 points and six rebounds for Quinnipiac. Ryan Mabrey also recorded 12 points. The Associated Press created this story using technology provided by Data Skrive and data from Sportradar .

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Amazon and Starbucks workers are on strike. Trump might have something to do with it Amazon delivery drivers and Starbucks baristas are on strike in a handful of U.S. cities as they seek to exert pressure on the two major companies to recognize them as unionized employees or to meet demands for an inaugural labor contract. Strikes during busy periods like the holidays can help unions exercise leverage during negotiations or garner support from sympathetic consumers. One expert says he thinks workers at both companies are “desperate” to make progress before President-elect Donald Trump can appoint a Republican majority to the National Labor Relations Board. Workers at Starbucks, Amazon and some other prominent consumer brands are fighting for their first contracts after several locations voted to unionize. Farmers are still reeling months after Hurricane Helene ravaged crops across the South LYONS, Ga. (AP) — Farmers in Georgia are still reeling more than two months after Hurricane Helene blew away cotton, destroyed ripened squash and cucumbers and uprooted pecan trees and timber. Agribusinesses in other Southern states saw costly damage as well. The University of Georgia estimates the September storm inflicted $5.5 billion in direct losses and indirect costs in Georgia alone. In rural Toombs County, Chris Hopkins just finished harvesting his ravaged cotton crop and figures he lost half of it, costing him about $430,000. Poultry grower Jeffrey Pridgen in Georgia's Coffee County had four of his 12 chicken houses destroyed and others badly damaged. Farmers say more government disaster assistance is needed. Ex-OpenAI engineer who raised legal concerns about the technology he helped build has died Suchir Balaji, a former OpenAI engineer and whistleblower who helped train the artificial intelligence systems behind ChatGPT and later said he believed those practices violated copyright law, has died, according to his parents and San Francisco officials. He was 26. He was well-regarded by colleagues at the San Francisco company, where a co-founder this week called him one of OpenAI’s strongest contributors who was essential to developing some of its products. But he grew disillusioned with the company and told The Associated Press this fall he would “try to testify” in copyright infringement cases against it. Federal Reserve's preferred inflation gauge shows price pressures eased last month WASHINGTON (AP) — An inflation gauge that is closely watched by the Federal Reserve barely rose last month in a sign that price pressures cooled after two months of sharp gains. Prices rose just 0.1% from October to November. Excluding the volatile food and energy categories, prices also ticked up just 0.1%, after two months of outsize 0.3% gains. The milder inflation figures arrived two days after Federal Reserve officials, led by Chair Jerome Powell, rocked financial markets by revealing that they now expect to cut their key interest rate just two times in 2025, down from four in their previous estimate. Albania to close TikTok for a year blaming it for promoting violence among children TIRANA, Albania (AP) — Albania’s prime minister says the government will shut down video service TikTok for one year, blaming it for inciting violence and bullying, especially among children. Albanian authorities held 1,300 meetings with teachers and parents following the stabbing death of a teenager in mid-November by another teenager following a quarrel that started on TikTok. Prime Minister Edi Rama, speaking at a meeting with teachers and parents, said TikTok “would be fully closed for all. ... There will be no TikTok in the Republic of Albania.” Rama says the ban will begin sometime next year. Albanian children comprise the largest group of TikTok users in the country, according to domestic researchers. Stock market today: Wall Street rises to turn a dismal week into just a bad one NEW YORK (AP) — U.S. stocks rose to turn what would have been one of the market’s worst weeks of the year into just a pretty bad one. The S&P 500 rallied 1.1% Friday to shave its loss for the week down to 2%. The Dow Jones Industrial Average jumped nearly 500 points, and the Nasdaq composite gained 1%. A report said a measure of inflation the Federal Reserve likes to use was slightly lower last month than expected. It’s an encouraging signal after the Fed shocked markets Wednesday by saying worries about inflation could keep it from cutting interest rates in 2025 as much as earlier thought. Starbucks workers begin strikes that could spread to hundreds of US stores by Christmas Eve Workers at U.S. Starbucks stores have begun a five-day strike to protest a lack of progress in contract negotiations with the company. The strikes began in Los Angeles, Chicago and Seattle and could spread to hundreds of stores across the country by Christmas Eve. Workers at 535 of the 10,000 company-owned Starbucks stores in the U.S. have voted to unionize. The Starbucks Workers United union accuses the Seattle-based coffeehouse chain of failing to honor a commitment made in February to reach a labor agreement this year. Starbucks says the union prematurely left the bargaining table this week. It said Friday there's been no significant impact to store operations. It's beginning to look like another record for holiday travel Drivers and airline passengers without reindeer and sleighs better make a dash for it: it’s beginning to look like another record for holiday travel in the U.S. The auto club AAA predicts that more than 119 million people will travel at least 50 miles from home between Saturday and New Year’s Day. The two weekends on either side of Christmas are tempting a lot of people to head out earlier. U.S. airlines expect to have their busiest days to be Friday and Sunday this week and next Thursday, Friday and Sunday. A government shutdown that could start as soon as Saturday was not expected to immediately affect flights and airport operations. Amazon workers are striking at multiple facilities. Here's what you should know Amazon workers affiliated with the Teamsters union are on strike for a second day at seven of the company’s delivery hubs just days before Christmas. At midnight on Saturday, the Teamsters say workers at a prominent unionized warehouse in New York will also join. The union has not indicated how many employees were participating in the walkout or when it will end. The Teamsters say the workers were continuing their strike on Friday after Amazon ignored a Sunday deadline the union had set for contract negotiations. The company says it doesn’t expect the strikes taking place in Southern California, San Francisco, New York City, Atlanta, and Skokie, Illinois, to impact holiday shipments. Alabama profits off prisoners who work at McDonald’s but deems them too dangerous for parole DADEVILLE, Ala. (AP) — No state has a longer, more profit-driven history of contracting prisoners out to private companies than Alabama. Best Western, Bama Budweiser and Burger King are among the more than 500 businesses to lease incarcerated workers from one of the most violent, overcrowded and unruly prison systems in the U.S. in the past five years alone, The Associated Press found as part of a two-year investigation into prison labor. The cheap, reliable labor force has generated more than $250 million for the state since 2000 — money garnished from prisoners’ paychecks. Kelly Betts of the corrections department defended the work programs, calling them crucial to the success of inmates preparing to leave prison, though she added some of the incarcerated workers are serving life without parole.

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NEW YORK (AP) — Keith Higgins Jr. had 16 points in Lehigh's 60-59 win over LIU on Saturday. Higgins also contributed three steals for the Mountain Hawks (4-6). Tyler Whitney-Sidney shot 4 for 12, including 2 for 5 from beyond the arc to add 11 points. Ben Knostman had 10 points and shot 3 of 4 from the field and 3 of 4 from the free-throw line. Jamal Fuller finished with 20 points and eight rebounds for the Sharks (4-11). LIU also got 16 points, 10 rebounds and three blocks from Shadrak Lasu. Blake Lander finished with 10 points. Higgins scored eight points in the first half and Lehigh went into the break trailing 35-28. Knostman led Lehigh with nine points in the second half as their team outscored LIU by eight points over the final half. Lehigh plays Neumann at home on Sunday, and LIU hosts Le Moyne on Friday. The Associated Press created this story using technology provided by Data Skrive and data from Sportradar .

Leader of the peopleRuud van Nistelrooy treated himself to a beer after enjoying a perfect start to his reign as Leicester manager. Van Nistelrooy’s first game in charge ended with a 3-1 win over West Ham, thanks to goals from Jamie Vardy, Bilal El Khannouss and Patson Daka. The Dutchman, who was out of work for just two weeks following his four-game spell as Manchester United interim boss, only started on Sunday so was happy to end a hectic three days in style. “It has been very busy getting to know everyone, start working together,” he said. “Everybody was involved with that and helping, it was busy, long days, but worth it. I was focused on the game and what the game needed, the subs, the half-time talk, so focused on the moment, so I am going to get myself a little beer and reflect on the last three days.” He endured a dream start as Vardy scored after just 98 seconds with El Khannouss and Daka adding second-half goals. It was by no means one-way traffic, though, as West Ham – who scored a consolation through Niclas Fullkrug at the death – had 30 shots on goal. But Van Nistelrooy saw enough to think he can deliver on his objective of keeping the Foxes in the Premier League. “I am very happy, if you look at the result – and it is about the result – it was a great night, three points, three good goals and also very effective. Ruud at the wheel 🛞 pic.twitter.com/eVgIwWAcYw — Leicester City (@LCFC) December 3, 2024 “Overall the game of course we have seen and how dominant West Ham were at certain stages and what they created, that is a fact and something we have to look at. “Overall, what I expected of the players going forward was togetherness and hunger, energy and spirit in this team that is fighting for every inch. “Eleven players on the pitch who are fighting as a foundation to play the rest of the Premier League. I saw that completely with every single player that started and came on. “That’s the foundation we have to build on, without that it will be impossible to get where we want to go. I am very happy about that.” West Ham’s hierarchy will have seen what impact a managerial change can have as the jury remains out on Julen Lopetegui, with away fans making their feelings clear by chanting “You’re getting sacked in the morning”. Lopetegui expects to keep his job but forthcoming games against his former club Wolves, Bournemouth, Brighton and Southampton could determine the Spaniard’s future. “The only thing that I am worried about is to go to training session tomorrow and stand up the players and prepare the next challenge,” he said. “We have one month of December with a lot of matches and I am sure with this attitude we are going to achieve many more points. “I believe in the players. I am confident that tomorrow we are going to be ready to prepare the next match. “Understanding the question, but at the end of the season maybe we talk in another way. There are a lot of matches and points, a lot of things can happen. “I believe in these players and team, I am sure the position is going to be much better. They are only words but we have to work a lot to achieve this.”

Happenings — what’s coming up in Northeast Ohio starting Dec. 27The AP Top 25 men’s college basketball poll is back every week throughout the season! Get the poll delivered straight to your inbox with AP Top 25 Poll Alerts. Sign up here . STONY BROOK, N.Y. (AP) — Joseph Octave scored 24 points as Stony Brook beat Maine 74-72 on Saturday. Octave also added five rebounds for the Seawolves (4-8). Ben Wight shot 4 of 7 from the field and 3 for 3 from the line to add 11 points. CJ Luster II shot 3 for 8 (2 for 5 from 3-point range) and 3 of 3 from the free-throw line to finish with 11 points. Kellen Tynes led the way for the Black Bears (8-6) with 15 points, four assists, four steals and two blocks. Jaden Clayton added 15 points, four assists and three steals for Maine. AJ Lopez finished with 13 points and four assists. Stony Brook went into halftime leading Maine 34-30. Octave put up 10 points in the half. Octave led Stony Brook with 14 points in the second half as his team was outscored by two points over the final half but held on for the victory. Both teams next play Sunday. Stony Brook visits Albany (NY) and Maine plays Boston University at home. ___ The Associated Press created this story using technology provided by Data Skrive and data from Sportradar .

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