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Forrest's 30 lead N.C. A&T past North Carolina Central 85-72AES Announces 2% Increase in Quarterly DividendShares of Arrowhead Pharmaceuticals Inc. ($ARWR) and Sarepta Therapeutics Inc. ($SRPT) climbed on Wednesday despite Wall Street trimming price targets after the companies announced a $1 billion licensing agreement. Under the deal, Sarepta gains exclusive global rights to multiple programs targeting rare genetic diseases affecting muscles, the central nervous system, and lungs. In return, Arrowhead will receive $825 million upfront, comprising $500 million in cash and $325 million in equity at a 35% premium. An additional $250 million will be paid in installments over the next five years. Arrowhead is also eligible for up to $10 billion in potential milestones and low double-digit royalties. Needham lowered Sarepta’s price target to $202 from $205, maintaining a ‘Buy’ rating. But the brokerage praised the deal for its platform diversification and alignment with Sarepta’s rare genetic medicine expertise. Piper Sandler cut Arrowhead’s price target to $45 from $62, keeping an ‘Overweight’ rating. The brokerage sees the collaboration as transformative, with Sarepta acquiring clinical and preclinical TRiM programs. Piper also reduced Sarepta’s price target to $182 from $200, highlighting the partnership’s pipeline expansion and near-term financial impact. Citi reduced Arrowhead’s price target to $26 from $27, maintaining a ‘Neutral’ stance. The analyst noted Arrowhead’s extended cash runway through 2028, aided by this deal and a strategic financing arrangement with Sixth Street. Arrowhead ranked among the top 10 trending symbols on Stocktwits by Wednesday afternoon, with a good dose of optimistic retail chatter driving activity for both stocks. However, a bearish overhang remains for Arrowhead after it missed fiscal fourth-quarter expectations on Tuesday, reporting a loss of $1.36 per share (vs. a $0.97 loss consensus) and $35 million in revenue (vs. $55.07 million expected). Arrowhead’s CEO emphasized the company’s readiness to commercialize medicines, spotlighting the recent submission of its first New Drug Application (NDA) to the FDA for plozasiran, which could launch in 2025 pending approval. Year-to-date, Arrowhead shares have declined over 14%, while Sarepta has surged more than 40%. For updates and corrections email newsroom[at]stocktwits[dot]com.<
NASSAU – Javon Small scored five of his 31 points in overtime and Tucker DeVries added key free throws late in regulation and finished with 16 points as West Virginia beat No. 3 Gonzaga 86-78 in the Battle 4 Atlantis on Wednesday. Small's layup with under 2 minutes left in OT gave West Virginia a 79-75 lead. After a Gonzaga miss, Sencire Harris hit two free throws to make it a six-point lead. With 27.1 seconds left, Harris made a steal and scored on a dunk for an eight-point lead, putting the game out of reach. Recommended Videos Amani Hansberry scored a career-high 19 points and Toby Okani added 10 for West Virginia (3-2). Braden Huff scored 19 points and Khalif Battle 16 for Gonzaga (5-1). Takeaways Gonzaga showed its depth, outscoring the West Virginia bench 30-2. West Virginia’s only loss was by 24 points at Pitt, but the rebuild under Darian DeVries is showing promise. Key moment Gonzaga turned it over at midcourt late in regulation when Tucker DeVries poked it away from Nolan Hickman and raced the other way before getting fouled. DeVries made two free throws with 5.9 seconds left to tie it at 71-all. Battle inbounded the ball and got it back, but lost control on a drive as time expired. Key stats The shorter Mountaineers outrebounded Gonzaga 42-36 and shot 50% in the second half, battling the Zags to a draw in the paint. Nembhard had 12 assists and just one turnover in 43 minutes, but was 1 of 10 from the field. Up next West Virginia will play Louisville on Thursday in the winner's bracket. Gonzaga faces No. 14 Indiana on the consolation side. ___ Get poll alerts and updates on the AP Top 25 throughout the season. Sign up here . AP college basketball: https://apnews.com/hub/ap-top-25-college-basketball-poll and https://apnews.com/hub/college-basketball
Chipotle is raising US prices after promising bigger portions
NoneIt's anybody guess when Linus Ullmark will return to Ottawa Senators netTrump's picks for key positions in his second administration
US President-elect Donald Trump has announced that retired Army general Keith Kellogg will be his special envoy for Ukraine and Russia. Trump is scheduled to be sworn in as the 47th US president on January 20 next year. He has already announced dozens of names of future officials, some of whom need to be approved by the Senate first. “He was with me right from the beginning,” Trump wrote on his Truth Social platform on Wednesday, announcing Kellogg’s nomination. “Together, we will secure peace through strength and make America, and the world, safe again!” Kellogg served as chief of staff for the National Security Council during Trump’s first presidential term (2017-2021). He was a top aide to then-Vice President Mike Pence and acting national security advisor to Trump after the ouster of General Michael Flynn in February 2017. ”I don’t think World War III has begun, but we’re right on the precipice,” Kellogg told Fox News last week , after President Joe Biden authorized long-range missile strikes into Russia. He described the conflict as “the largest land war in Europe since the end of WWII,” where a single spark “can spin things right out of control, without even trying.” Kellogg did not criticize the White House for making the missile decision, however, saying that it would give Trump “more leverage” to negotiate come January. Richard Grenell, the former US ambassador to Germany and Trump’s former acting director of national intelligence, had also been a candidate for the job. According to Reuters, Kellog and another former Trump aide, Fred Fleitz, co-authored the proposal for ending the Russia-Ukraine conflict that Vice President-elect JD Vance outlined in a September interview. The plan would freeze the conflict along the current line of confrontation without recognizing Russia’s sovereignty over territories claimed by Ukraine, while putting off consideration of Kiev’s membership in NATO for a future date. Moscow would be forced to the negotiating table by a threat of US increasing its aid to Kiev, while Ukraine would get a promise of more American weapons if it agreed to the talks. Both Russia and Ukraine have dismissed the rumored proposal as a non-starter, however. Kellogg served in the US Army and was chief of staff of the 82nd Airborne Division during the first Gulf War (1990-1991). After the 2003 US invasion of Iraq, he was appointed chief operating officer of the occupation authority in Baghdad.Food inflation has significant and far-reaching consequences for individual countries and the global economy as a whole. A large portion of income in developing nations is spent on food. Therefore, rising prices force households to cut back on nutrition, worsening malnutrition and poverty. Net food-importing countries experience trade deficits, while exporting nations see temporary surpluses. Rising prices have seen disrupting global trade flows as countries impose export bans to secure domestic supply. Food inflation, obviously, contributes to global inflation, complicating policy decisions for central banks and increasing borrowing costs worldwide. A recent World Bank report has shown domestic food price inflation remains high in many low- and middle-income countries. Inflation higher than 5% is experienced in 68.8% of low-income countries (1.2 percentage points lower since the last update on November 15, 2024), 46.7% of lower-middle-income countries (1.1 percentage points lower), 33% of upper-middle-income countries (3.0 percentage points lower), and 10.9% of high-income countries (1.8 percentage points higher). In real terms, food price inflation exceeded overall inflation in 59.8% of the 164 countries where data is available. In the November 2024 edition of its biannual ‘Food Outlook’, UN’s Food and Agricultural Organisation (FAO) indicates that global food production is experiencing diverse trends across commodities. Declines are projected for wheat, maize, and sugar, whereas outputs of dairy, fisheries, meats, oilseeds, and rice are expected to grow. These shifts have implications for global consumption, trade, and stock levels, although food production remains highly sensitive to disruptions from adverse weather conditions, geopolitical conflicts, and policy changes. These factors threaten the balance between supply and demand, potentially undermining global food security. The ‘food outlook’ also describes significant changes in the fertilizer market. After a challenging 2022 marked by high costs and limited production, 2023 saw notable recovery. In 2024, nitrogen production is expected to remain stable, phosphate production to decline slightly, and potassium to continue its growth trajectory. Lower natural gas prices, a key input for nitrogen fertilisers, have been instrumental in stabilising production costs. According to the WFP 2025 Global Outlook, an estimated 343mn people are acutely food insecure across 74 countries where WFP operates—10% more than in 2023 and nearly 200mn more than before the pandemic. An estimated 1.9mn people are on the brink of famine in 2024, primarily in Gaza and Sudan but also in Haiti, Mali, and pockets of South Sudan. Conflict, economic factors, and climate remain the main drivers of food insecurity, with 65% of acutely food-insecure people living in fragile or conflict-affected situations. Following the Russia - Ukraine war, trade-related policies imposed by countries have surged. The global food crisis has been partially made worse by the growing number of food and fertiliser trade restrictions put in place by countries with a goal of increasing domestic supply and reducing prices. As of this month, some 17 countries have implemented as many as 22 food export bans, and eight have implemented 12 export-limiting measures. Food inflation is not only an economic challenge but also a humanitarian and geopolitical issue. Therefore, coordinated global efforts are crucial to mitigate its impact on vulnerable populations and ensure food security. 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emicide, or the killing of a woman or girl by a man, typically because of her gender, and other incidents of gender-based violence regularly make national and local headlines in the country. The problem seems to have worsened rapidly in recent years. Certainly news coverage of the issue has become more prevalent, thanks in part to wider access to the internet and social media in the country. The National Commission on Violence Against Women (Komnas Perempuan) recorded 95 cases of femicide in the country in 2020. In the following two years, the figure rose to 237 then 307. Although the number of recorded femicides dropped last year to 159, many women’s rights groups believe that what they describe as “the most extreme form of gender-based violence” will never end if law enforcement remains apathetic about such cases, paving the way for recurring offenses. Often, when victims of gender-based violence seek help from the police, they are faced with resistance, convoluted procedures or, even worse, accusations that they brought the crimes upon themselves because of the way they dressed or behaved. Furthermore, a number of victims have reportedly experienced additional sexual offenses from police officers themselves when filing their reports. Whether you're looking to broaden your horizons or stay informed on the latest developments, "Viewpoint" is the perfect source for anyone seeking to engage with the issues that matter most. By registering, you agree with 's Please check your email for your newsletter subscription. In May, a member of the Tanjung Pandan Police in Bangka Belitung Islands, identified as Brig. AK, reportedly molested a junior high school student reporting an alleged rape by the caretaker of the orphanage where she had lived for two years. This is not the only case of sexual harassment by law enforcement officers, as each year, the Commission for Missing Persons and Victims of Violence (Kontras) receives similar reports. This dire situation has stopped an unknowable number of victims from speaking up, leaving them open to repeated violence, often in their own homes and perpetrated by people within their close circles. Last year, Komnas Perempuan recorded approximately 290,000 instances of violence against women across the country, around 98 percent of which took place “in the domestic sphere”. The home, which should be a safe space for women, was main scene of such violence, the report noted. The United Nations’ gender equality and women’s empowerment body, known as UN Women, reported recently that 140 women and girls died every day at the hands of close relatives or partners, underlining the global crisis of gender-based violence and the urgent need for quick action. The UN Women report was published on Nov. 25 to coincide with the annual 16 days of activism against gender-based violence. The date was selected to honor the Mirabal sisters, three political activists from the Dominican Republic who were brutally murdered in 1960 by order of the country’s ruler. Fortunately, there is hope in Indonesia. Prevailing Indonesian regulations, such as the 2022 Sexual Violence Eradication Law and the 2004 Domestic Violence Eradication Law, have laid the foundations for the government and law enforcement to handle cases of violence against women, including by offering protection and assistance as soon as the victims file their reports. The 2022 law even calls for the establishment of regional technical management units for the protection of women and children, as well as integrated education and training for law enforcement on the handling of sexual violence cases. Problems, however, persist in the implementation of the laws and in the lack of commitment from authorities to give the victims proper consideration. Justice for victims of gender-based violence can only be achieved if all of their rights are fulfilled and the perpetrators are reliably held accountable and handed just punishments. We call for zero tolerance of gender-based violence, as well as for femicide to be distinguished from other forms murder in the country’s legal system to provide a greater deterrent effect.Nissan and Honda materialize merger of both car companies
Sabrina Ionescu was thrilled to be part of Unrivaled — the The Liberty star guard who helped New York win the first championship in franchise history earlier this year signed a historic agreement on Monday with the league. She'll join the Phantom BC that Saturday night to acquire Natasha Cloud. "It was a huge decision getting me to play or not," Ionescu said in a phone interview Monday night. "I weighed out all my options and decided to do what’s best for me and my career. Being able to take part in a league that is the first of its kind with a historic deal and be on the ownership side of it is important for me.” Ionescu said the league gave her some flexibility in her schedule if she needs to step away for a day or two. The NBA All-Star Game is on Feb. 16, which is in the middle of the Unrivaled season. The league has no team games during the NBA All-Star weekend. There's discussions of her potentially competing in another 3-point contest with Stephen Curry. “I have certain dates that I have to be gone for. They were very accommodating with things I already accepted and have to be gone for before I committed to the league,” Ionescu said. Ionescu will also be playing with Brittney Griner, Marina Mabrey, Katie Lou Samuelson and Satou Sabally. Ionescu was teammates with Sabally at Oregon. “I’m really excited being able to play with her and knowing we’ve wanted to play with each other for a long time since we departed from Oregon,” Ionescu said. The 27-year-old Ionescu is she had earlier this month on her right thumb to stabilize the ulnar collateral ligament. She's not cleared yet, but is on target to be able to play at the start of the Unrivaled season. “I should be cleared and ready to go and be able to be there and be a part of it,” Ionescu said. “The first year was something I wanted to experience and have ownership is a big part in that as well.” Ionescu said she hurt the thumb in the final 90 seconds of Game 4 of the WNBA Finals, but there was no way she was going to miss the decisive Finals game which New York won. She went 1 for 19 in against Minnesota but found other ways to help the team win, with eight assists and seven rebounds. “I didn’t know the severity of my injury when I did it. I didn’t care to know and wanted to do whatever I could to play and try to do the best I can for us to win,” she said. “Thankfully I was able to do everything beside shooting which now makes a lot of sense since I couldn’t grip a basketball.” Ionescu took a few weeks to see if the injury would heal on its own after the season was over. She got a few opinions from doctors before deciding that surgery was the best option. This is the first time that Ionescu is taking part in an offseason league. “I’m excited. Obviously it's a great opportunity to be able to play and continue to refine my game in the offseason," she said. “It’s a great opportunity to compete against the best players in the league that are now in Unrivaled.” It has been a busy year for the former Oregon great, who also got married and . “It’s been amazing. When I sit back and think about everything that happened this year, it puts a lot in perspective when things aren’t going as well,” she said. “I've had those years where everything was going wrong and then to have a year like this where you stop and smell the roses and everything you prayed and wished for happens.” ___ AP WNBA: Doug Feinberg, The Associated PressNone
Injuries pile up, 49ers uncertain QB Brock Purdy can return Sunday
When Esha Deol slapped Amrita Rao on Pyaare Mohan setOTTAWA—Brampton Mayor Patrick Brown said he received pushback from Indian government officials for his use of the term “Sikh nation” during the 2022 Conservative leadership campaign, but generally believes that foreign interference did not alter the outcome of the race. Brown was called to testify before the House of Commons public safety committee on Thursday evening. The committee is studying the Indian government’s involvement in political interference and violence in Canada. Brown initially declined an invitation to appear, but was formally summoned. He said he didn’t want to be part of any political wrangling. “I don’t have an interest in revisiting partisan debates.” A Radio-Canada story earlier this week reported that insiders on Brown’s Conservative leadership campaign felt the Indian government was interfering, trying to undermine his campaign. This included disinviting him from events in the community and encouraging volunteers not to support him. The story also alleged that Calgary MP Michelle Rempel Garner was encouraged by Indian consular officials to drop her support for Brown. Brown said on a campaign call he was told the Indian government rejected the term “Sikh nation,” which he had used in public remarks. “The concern that was raised was that I had used the term, on a number of occasions, Sikh nation, and the consul general had expressed directly to MP Rempel Garner that was something that obviously they didn’t agree with,” he said. Some members of the Sikh community in Canada favour the creation of a separate state in India called Khalistan that would be a homeland for their community, but the Indian government firmly rejects that idea. Brown said he used a different term than “Sikh nation” after the Indian government complained, and downplayed the importance of the wording change, but Liberal MP Jennifer O’Connell said she saw it as a clear example of interference. “I think that constitutes foreign interference, pretty clearly. With foreign interference it doesn’t matter the outcome. It’s the intention to have the foreign government influence the actions in Canadian elections.” Brown also said, in contrast to the Radio-Canada reporting, Rempel-Garner never indicated she was leaving because of any foreign pressure. “At no point when we talked about her departing the campaign did she say it was because of pressure from the consul general,” he said. At the end of the meeting, O’Connell moved to have Rempel Garner and several members of the Brown campaign called to testify. O’Connell’s motion will be voted on at a later meeting. Brown said when he was a provincial party leader he supported motions recognizing a 1984 attack on Sikh communities as a genocide and spoke out about some of the actions of the Indian government. He said Indian diplomats aren’t quiet about their opinions. “I think it’s fair to say that the government of India states their opinions and I think there’s a number of issues that I took a position on that certainly the Government of India wasn’t a fan of,” he said. Brown was disqualified from the Conservative leadership over allegations he had breached the party’s campaign finance rules. Brown said he had no direct knowledge of foreign interference in his campaign. He said he was aware of one community event where he was disinvited, but said he has no doubt the outcome of the race would have been the same. “I believe that Pierre Poilievre was successful in that race because he signed 300,000 plus memberships. And, I don’t believe acts of foreign intervention affected that result.” Brown’s community has a significant Sikh population and he said there is a lot of ongoing concern about India and other countries interfering in Canada. The committee has also heard testimony from the RCMP and other security agencies about the Indian government’s involvement in a campaign of violence in Canada. This has included the killing of Hardeep Singh Nijjar in Surrey, B.C., which Brown said is a major concern for the community. He said he believes — to start with — the federal government needs to clearly outline the rules to foreign diplomats who are crossing the lines. “A starting point is a clear education on those who are serving as diplomatic representatives in Canada of what is appropriate behaviour and behaviour that is inappropriate with the laws we have in Canada, clearly there are diplomats that need that education,” he said.
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ENGLEWOOD, Colo. (AP) — John Elway says any remorse over bypassing Josh Allen in the 2018 NFL draft is quickly dissipating with rookie Bo Nix's rapid rise, suggesting the Denver Broncos have finally found their next franchise quarterback. Elway said Nix, the sixth passer selected in April's draft, is an ideal fit in Denver with coach Sean Payton navigating his transition to the pros and Vance Joseph's defense serving as a pressure release valve for the former Oregon QB. “We’ve seen the progression of Bo in continuing to get better and better each week and Sean giving him more each week and trusting him more and more to where last week we saw his best game of the year,” Elway said in a nod to Nix's first game with 300 yards and four touchdown throws in a rout of Atlanta. For that performance, Nix earned his second straight NFL Rookie of the Week honor along with the AFC Offensive Player of the Week award. “I think the sky’s the limit," Elway said, “and that’s just going to continue to get better and better.” In a wide-ranging interview with The Associated Press, Elway also touted former coach Mike Shanahan's Hall of Fame credentials, spoke about the future of University of Colorado star and Heisman favorite Travis Hunter and discussed his ongoing bout with a chronic hand condition. Elway spent the last half of his decade as the Broncos’ GM in a futile search for a worthy successor to Peyton Manning, a pursuit that continued as he transitioned into a two-year consultant role that ended after the 2022 season. “You have all these young quarterbacks and you look at the ones that make it and the ones that don’t and it’s so important to have the right system and a coach that really knows how to tutelage quarterbacks, and Sean’s really good at that,” Elway said. “I think the combination of Bo’s maturity, having started 61 games in college, his athletic ability and his knowledge of the game has been such a tremendous help for him,'" Elway added. “But also Vance Joseph’s done a heck of a job on the defensive side to where all that pressure’s not being put on Bo and the offense to score all the time.” Payton and his staff have methodically expanded Nix’s repertoire and incorporated his speed into their blueprints. Elway lauded them for “what they’re doing offensively and how they’re breaking Bo into the NFL because it’s a huge jump and I think patience is something that goes a long way in the NFL when it comes down to quarterbacks.” Elway said he hopes to sit down with Nix at some point when things slow down for the rookie. Nix, whose six wins are one more than Elway had as a rookie, said he looks forward to meeting the man who won two Super Bowls during his Hall of Fame playing career and another from the front office. “He’s a legend not only here for this organization, but for the entire NFL," Nix said, adding, "most guys, they would love to have a chat with John Elway, just pick his brain. It’s just awesome that I’m even in that situation.” Hall of Fame Orange Crush linebacker Randy Gradishar joined Elway in the Pro Football Hall of Fame this year, something Elway called “way, way overdue.” Elway suggested it's also long past time for the Hall to honor Shanahan, who won back-to-back Super Bowls in Denver with Elway at QB and whose footprint you see every weekend in the NFL because of his expansive coaching tree. Sanders & Hunter Elway called University of Colorado stars Travis Hunter and Shedeur Sanders “both great athletes." He said he really hopes Sanders gets drafted by a team that will bring him along like the Broncos have done with Nix and he sees Hunter being able to play both ways in the pros but not full time. Elway said he thinks Hunter will be primarily a corner in the NFL but with significant contributions on offense: “He's great at both. He's got great instincts, and that's what you need at corner." Hand condition It's been five years since Elway announced he was dealing with Dupuytren’s contracture, a chronic condition that typically appears after age 40 and causes one or more fingers to permanently bend toward the palm. Elway's ring fingers on both hands were originally affected and he said now the middle finger on his right hand is starting to pull forward. So, he’ll get another injection of a drug called Xiaflex, which is the only FDA-approved non-surgical treatment, one that he's endorsing in an awareness campaign for the chronic condition that affects 17 million Americans. The condition can make it difficult to do everyday tasks such as shaking hands or picking up a coffee mug. Elway said what bothered him most was “I couldn't pick up a football and I could not imagine not being able to put my hand around a football." ___ AP NFL: https://apnews.com/hub/nfl Arnie Stapleton, The Associated Press
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