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ICC Champions Trophy 2025 Schedule: India vs Pakistan Match Set for February 23 in Dubai
Jefferson keeps seeing double as Vikings aim to stay focused on overall offensive productionSuitcase killer Sarah Boone sentenced to life for boyfriend’s murderEAGAN, Minn. (AP) — Justin Jefferson might be weary of all the safeties shadowing his every route, determined not to let the Minnesota Vikings go deep, but he's hardly angry. The double and triple coverage he continually faces, after all, is a sign of immense respect for his game-breaking ability. The strategy also simply makes sense. Javascript is required for you to be able to read premium content. Please enable it in your browser settings. Get any of our free email newsletters — news headlines, obituaries, sports, and more.
The U.S. Food Drug Administration (FDA) has granted accelerated approval of a new drug for treating bilary tract cancer that was developed by Vancouver’ s Zymeworks Inc. (Nasdaq: ZYME) under a licensing and commercialization agreement with Jazz Pharmaceuticals. The new drug, Ziihera, could net Zymeworks more than $1 billion just in milestone payments, and millions more in royalties, upon full commercialization. Gaining the FDA’s accelerated approval triggers a $25 million milestone payment to Zymeworks from Jazz Pharmaceuticals – the first of more to come, should other milestones be reached. Under its licensing agreement, Zymeworks is eligible for up to $500 million in regulatory milestones, $862.5 million in commercial milestone payments, and royalties of 10 to 20 per cent on sales. “This approval represents the first FDA-approved therapy in Zymeworks’ pipeline, and validates the company’s novel Azymetric bispecific platform technology and internal research and development capabilities for novel multifunctional medicines,” Zymeworks says in a news release. “The FDA’s accelerated approval of Ziihera marks the culmination of more than a decade of research and development at Zymeworks, highlighting our deep scientific expertise in multifunctional biotherapeutics and unwavering commitment to innovation in drug development,” said Paul Moore, Zymeworks’ chief science officer. Ziihera is one of several variations of the bispecific antibody Zanidatamab that Zymeworks developed for treating various types of cancer, and one of three in the advanced “pivotal” trial phase. Several others are at phase 2 in clinical trials. In 2022, Zymeworks entered a licence and collaboration agreement with Jazz Pharmaceuticals Ireland Ltd -- a subsidiary of Jazz Pharmaceuticals plc -- for the exclusive development and commercialization rights to Zanidatamab in the U.S., Europe, Japan and other countries. A study published last year in The Lancet concluded that Zanidatamab “demonstrated meaningful clinical benefit with a manageable safety profile in patients with treatment-refractory, HER2-positive biliary tract cancer.” [email protected] twitter.com/nbennett_biv
A leading surgeon left feeling “exhausted and burdened” after working tirelessly for 70 hours per week has revealed the “revolutionary” tool that has changed his life. Dr. Michael Ewing shared a video on LinkedIn earlier this week, detailing how the product has not only given him back precious time with his family and children – but also saved patients’ lives . Like many doctors, the 36-year-old dad spent his residency overworked, l ogging hundreds of hours . Much of Dr Ewing’s workload was actually down to endless charting, rather than focusing on his true passion: patient care. McDonald's fans share secret hack for making famous chicken nuggets extra crispy Home chef shares 'flu bomb' recipe that 'gets rid of illness in just three days' He longed to find a solution to have the capacity to be more present and now, he’s found it, through a “game-changing” tool called SurgeOn Scribe , launching today (10 December). Using AI technology, the feature automates the clinical documentation process – cutting down on mistakes, saving time and also whittling out the likelihood of any legal problems. “Doctors want to help people – that’s why we chose this path – but we are forced to spend so much time charting, when all we really want to do is to talk and listen to our patients,” said Dr Ewing. “I see about 50-60 patients a week and I have to remember small details, regardless of the situation," he said. “But doctors are only human – there’s a lot of mental stress and a lot of time that’s wasted by trying to recount visits. “On top of that, we are constantly being pulled in multiple directions and there’s always another emergency going on." He added “I save at least an hour a day in the clinic now and I can’t tell you how valuable it is for my mental capacity. Not only that, but I now spend 95% of patient visits listening to what patients are saying rather than making mental notes or being distracted by the demands of charting." “Reviewing my own experience, I calculated that saving time on chart notes could allow surgeons to see up to an additional seven people per day in a half-day clinic," he claimed. “This AI tool will save patient’s lives.” Growing up, Dr. Ewing, who is originally from Dallas, Texas, actually wanted to be a professional guitar player. He was working in an ER while studying music at the Dallas Baptist University, when he became fascinated by the medical profession – which led him to switch courses completely. The doctor said: “I had been working as a scribe to make extra money but didn’t expect to be so inspired by how physicians worked with their hands." “Surgery specifically has the ability to cure people in certain situations and this spoke to me," he said. "So I switched college tracts, which was not easy." “Surgical training is exhausting and surgical life as an attending is even more exhausting due to the constant demands of patients, continued Ewing. “It keeps you from your family and there is also a mental strain. “Now, with SurgeOn Scribe, I get home an hour earlier twice a week, allowing me to see my children more," he championed.“I can also take an extra day off every month, which is life-changing for my family." “Time is my most valuable asset and this tool gives it to me in droves.” With burnout becoming more common in the medical field, Dr.Ewing knew there must be a better way of working and found himself wanting to do something to help. His feelings were echoed by three other surgeons in the field; Dr Jeremy Heffner, Dr.Mario Leyba and Dr. Mark Soliman. The trio founded the app SurgeOn, with the aim of putting an end to the “isolation” felt universally among surgeons. It allows medical professionals to share cases and complexities of a job that most non-surgeons have a tough time relating to. But more needed to be done and that’s when Scribe was born. The new feature, which is found within the app and is launching today, hopes to provide a better patient experience. It allows users to transcribe medical notes either straight onto the computer or, if connectivity is low, onto an Apple Watch. Partnering with MedQuill, an AI-powered medical documentation platform that Dr Ewing helped create, this new product will help SurgeOn’s network of over 15,000 surgeons get their lives back. “For surgeons, our work-life balance is dictated by others more than people realize,” added Dr. Heffner, co-founder of SurgeOn. “Note writing and documentation has eaten up a significant portion of our lives. For the first time in years, we can truly connect with patients and have meaningful conversations with them." “I also have more time to be with my family, and maintain my own fitness levels and mental health," he added “As I age I have truly realised the value of time as a commodity, therefore having more time is priceless.” DAILY NEWSLETTER: Sign up here to get the latest news and updates from the Mirror US straight to your inbox with our FREE newsletter.Cowboys linebacker DeMarvion Overshown could miss 2025 season after latest knee injury, coach says
James Gunn Talks ‘Creature Commandos’ and ‘Superman’: “David Corenswet Is Going to Freak Everyone Out”
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