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Ying Tang / NurPhoto via Getty Images GameStop ( GME ) swung to a profit in the third quarter, even as revenue fell year-over-year. Shares surged in extended trading Tuesday on the news. The video game retailer posted a profit of $17.4 million or 4 cents per share on revenue of $860.3 million, compared with a loss of $3.1 million or 1 cent per share on revenue of $1.08 billion a year ago. GameStop isn't widely covered by Wall Street, with Wedbush's Michael Pachter the lone analyst tracked by Visible Alpha. In a note Friday he reiterated an "underperform" rating and $10 price target for the stock, writing that "the company's planned return to growth faces insurmountable barriers." GameStop was in the meme stock spotlight again last week, when a cryptic post on X from social media influencer Keith Gill—better known as "Roaring Kitty" —sent the stock as much as 14% higher Thursday afternoon in a short-lived spike. GameStop shares, which popped over 10% in extended trading, were up about 54% for 2024 through Tuesday's close. Most of the gains this year came in May and June after Gill posted about the retailer on multiple occasions for the first time since a meme trading frenzy gripped the stock in late 2020 and early 2021. Read the original article on Investopedia
SAN JOSE, Calif., Dec. 10, 2024 (GLOBE NEWSWIRE) -- Nutanix, Inc. ("Nutanix") NTNX , a leader in hybrid multicloud computing, today announced its intention to offer, subject to market conditions and other factors, $750 million aggregate principal amount of convertible senior notes due 2029 (the "notes") in a private placement (the "offering") to persons reasonably believed to be qualified institutional buyers pursuant to Rule 144A under the Securities Act of 1933, as amended (the "Securities Act"). Nutanix also expects to grant the initial purchasers of the notes an option to purchase up to an additional $112.5 million aggregate principal amount of the notes within a 13-day period from, and including, the initial issuance date of the notes. The notes will be unsecured senior obligations of Nutanix. Interest will be payable semi-annually in arrears. The notes will mature on December 15, 2029, unless earlier converted, redeemed, or repurchased. The notes will be convertible at the option of holders, subject to certain conditions and during certain periods. Upon conversion, the notes may be settled in cash, shares of Nutanix's Class A common stock or a combination of cash and shares of Nutanix's Class A common stock, at Nutanix's election. The interest rate, initial conversion rate and other terms of the notes are to be determined at the time of the pricing of the offering. Nutanix intends to use the net proceeds from the offering to (i) repurchase a portion of its outstanding 0.25% Convertible Senior Notes due 2027 (the "2027 notes") concurrently with the pricing of the offering in separate and privately negotiated transactions with certain holders of its 2027 notes (the "concurrent note repurchases") effected through one of the initial purchasers of the notes or its affiliate, acting as Nutanix's agent, and (ii) repurchase up to $200.0 million of shares of Nutanix's Class A common stock in privately negotiated transactions with institutional investors effected through one of the initial purchasers of the notes or its affiliate, acting as Nutanix's agent, at a price per share equal to the last reported sale price of Nutanix's Class A common stock on the Nasdaq Global Select Market on the date of the pricing of the notes (the "Share Repurchase"). Any such Share Repurchase would not reduce the amount available for future repurchases under Nutanix's existing share repurchase program. Nutanix intends to use the remaining net proceeds from the offering for general corporate purposes, including working capital, capital expenditures and potential acquisitions. From time to time, Nutanix evaluates potential acquisitions of businesses, technologies or products. Currently, however, Nutanix does not have any understandings or agreements with respect to any acquisitions. The terms of the concurrent note repurchases are anticipated to be individually negotiated with each holder of the 2027 notes participating in the concurrent note repurchases, and will depend on several factors, including the market price of Nutanix's Class A common stock and the trading price of the 2027 notes at the time of each such concurrent note repurchase. Certain holders of any 2027 notes that Nutanix agrees to repurchase may have hedged their equity price risk with respect to such 2027 notes and may, concurrently with the pricing of the notes, unwind all or part of their hedge positions by buying Nutanix's Class A common stock and/or entering into or unwinding various derivative transactions with respect to Nutanix's Class A common stock. Any repurchase of the 2027 notes, and the potential related market activities by holders of the 2027 notes participating in the concurrent note repurchases, together with the repurchase by Nutanix of any of its Class A common stock concurrently with the pricing of the notes, could increase (or reduce the size of any decrease in) the market price of Nutanix's Class A common stock, which may affect the trading price of the notes at that time and the initial conversion price of the notes. Nutanix cannot predict the magnitude of such market activity or the overall effect it will have on the price of the notes or its Class A common stock. No assurance can be given as to how much, if any, of the 2027 notes or the Class A common stock will be repurchased or the terms on which they will be repurchased. Neither the notes nor the shares of Nutanix's Class A common stock potentially issuable upon conversion of the notes, if any, have been, or will be, registered under the Securities Act or the securities laws of any other jurisdiction, and unless so registered, may not be offered or sold in the United States, except pursuant to an applicable exemption from, or in a transaction not subject to, such registration requirements. This announcement is neither an offer to sell nor a solicitation of an offer to buy any of these securities and shall not constitute an offer, solicitation, or sale in any jurisdiction in which such offer, solicitation, or sale is unlawful. About Nutanix Nutanix is a global leader in cloud software, offering organizations a single platform for running applications and managing data, anywhere. With Nutanix, companies can reduce complexity and simplify operations, freeing them to focus on their business outcomes. Building on its legacy as the pioneer of hyperconverged infrastructure, Nutanix is trusted by companies worldwide to power hybrid multicloud environments consistently, simply, and cost-effectively. Forward-Looking Statements This press release includes forward-looking statements within the meaning of Section 27A of the Securities Act and Section 21E of the Securities Exchange Act of 1934, as amended, including statements regarding Nutanix's financing plans, Nutanix's ability to complete the offering, the timing and size of the offering, the concurrent note repurchases and the Share Repurchase, Nutanix's intended use of the net proceeds of the offering. These statements involve risks and uncertainties that could cause actual results to differ materially, including, but not limited to, whether Nutanix will be able to consummate the offering, the final terms of the offering, the satisfaction of customary closing conditions with respect to the offering of the notes, prevailing market conditions, the anticipated use of the net proceeds of the offering of the notes, which could change as a result of market conditions or for other reasons, and the impact of general economic, industry or political conditions in the United States or internationally. Forward-looking statements may be identified by the use of the words "may," "will," "expect," "intend," and other similar expressions. These forward-looking statements are based on estimates and assumptions by Nutanix's management that, although believed to be reasonable, are inherently uncertain and subject to a number of risks. Actual results may differ materially from those anticipated or predicted by Nutanix's forward-looking statements. All forward-looking statements are subject to other risks detailed in Nutanix's Annual Report on Form 10-K for the fiscal year ended July 31, 2024, and the risks discussed in Nutanix's other filings with the Securities and Exchange Commission. You are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date hereof. All forward-looking statements are qualified in their entirety by this cautionary statement, and Nutanix undertakes no obligation to revise or update this news release to reflect events or circumstances after the date hereof, except as required by applicable law. © 2024 Nutanix, Inc. All rights reserved. Nutanix, the Nutanix logo, and all Nutanix product and service names mentioned herein are registered trademarks or unregistered trademarks of Nutanix, Inc. ("Nutanix") in the United States and other countries. Other brand names or marks mentioned herein are for identification purposes only and may be the trademarks of their respective holder(s). This press release is for informational purposes only and nothing herein constitutes a warranty or other binding commitment by Nutanix. Investor Contact: Richard Valera ir@nutanix.com Media Contact: Lia Bigano pr@nutanix.com © 2024 Benzinga.com. Benzinga does not provide investment advice. All rights reserved.New Report Finds Bioscience Sector Generates Over $3 Trillion for U.S. EconomyWithin hours of the murder of United Healthcare CEO Brian Thompson in New York City earlier this week, the surveillance video that captured the brazen crime made the rounds across social media. Across X, Reddit and Facebook, the short video was likely analyzed as closely as the footage of the assassination of President John F. Kennedy just over 61 years ago. And like that infamous shooting, the one in Midtown Manhattan has led to no shortage of conspiracy theories that are now making the rounds on the social platforms. Online sleuths offered their unsolicited opinions, while countless "experts" provided unique insight—with some suggesting the murder was carried out by a professional hit man, who not only used a suppressor but likely subsonic ammunition, which necessitated the need to manually operate the handgun's slide. Some even identified the firearm as a Welrod , a British bolt-action, magazine-fed, suppressed pistol devised during the Second World War, while others said it was likely a B&T VP9. Neither is likely the case. Moreover, the professional killer theories were in stark contrast to the New York Police Department's claim that the suspect's firearm had jammed, and he left several clues that could help the investigation. "Experts" Are Quick To Weigh In Armchair generals and Monday morning quarterbacks are all too common in our modern era—they're the individuals who quickly offer opinions after the fact, and typically with the benefit of hindsight. Social media is filled with these so-called experts, many who have built massive followings. As fresh details surrounding Thompson's murder were released, it only served to fuel the online speculation. The case already has the potential to be like a true crime podcast that unfolds in real-time. Yet, it also is clear that there is likely far more misinformation spreading than actual facts. "The amount of information that is out is inconsistent and much of it is inaccurate," said Dr. Dan Ariely, professor of psychology and behavioral economics at Duke University. "This does a very large disservice to society." Ariely warned that in situations like this still ongoing investigation, it has the potential to erode trust in the mainstream media, which often waits for confirmation. Social media by contrast is quick to post, even if the information is wrong. Beyond the fact that an individual was killed on the streets of America's largest city, this casual posting online often lacks perspective, and fact-checking and is too quick to rely on guesswork—and without much of the evidence that the NYPD has access to. "All this speculation is problematic because it sets expectations that may not be met," explained technology industry analyst Rob Enderle of the Enderle Group. "We are making conclusions before we have all the facts and 'Confirmation Bias' tells us that is a bad thing because people will then only recognize facts or theories that are consistent with the position they have already taken," Enderle added. "It is shoot, ready, aim, instead of what should be ready, aim, shoot." Vetting Sources Closer inspection of the video, as well as the shell casings and unspent round that was recovered; it has been determined that the firearm almost certainly used by the assailant wasn't the aforementioned Welrod or B&T VP9. Nor was the ammunition subsonic. Likewise, given that the shooter's movements have been traced—including to a Starbucks, where he bought a bottle of water and energy bars—it would seem that he wasn't likely a professional assassin. Few hit men would likely stop to pick up breakfast and be caught on camera. Still, it is all too easy to forgive those who are quick to post such misinformation, because of a desire to want to know the facts as quickly as they unfold. Newsrooms seek not to be first, but to get it right—whereas on social media there is a race to share that expert insight as quickly as possible. "We have all become expert crime solvers on social media, especially when there is a compelling and surprising crime such as the shooting death of this health insurance executive," said Susan Campbell, distinguished lecturer in the Department of Communication, Film, and Media Studies at the University of New Haven. "There will always be a lag time between new developments and publication of those developments in traditional media because traditional media worth its salt will still take time to vet the facts," Campbell added. "If people want to hear guesses quickly, social media is their platform. If they want to know facts, that takes a little more time." How Conspiracies Are Born The final concern is that the posts on social media will only serve to give rise to unfounded conspiracy theories that are impossible to debunk. Even after more than two decades, some still question the events of 9/11, and after six decades, the assassination of JFK continues to be debated. This is largely harmless, at least until it isn't. "There will also be efforts after facts are collected to ignore those that counter already taken positions," said Enderle. "In effect, this speculation corrupts the process and makes it less likely we'll ever see the truth. So, in general, social speculation doesn't help the process, it corrupts it." While it could impact the ability to bring an individual to justice, it also serves as another divide in our already deeply divided nation. "Sadly, everything is becoming political," said Ariely. "Right now, people aren't coming from the facts, but rather from a specific point of view. We need to figure out how to look at facts rather than identity."None
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AP Business SummaryBrief at 3:46 p.m. ESTCritical Metals Corp. Appointment of CFO and Board TransitionIT was a typically sunny Los Angeles afternoon and I was sitting in a trailer at the ABC Studios car park watching Bruno Tonioli strip down to his underpants. Bruno was all hot and bothered after a full afternoon rehearsing for Dancing With The Stars, the US version of the show that made him a household name, Strictly Come Dancing. 6 I had only met Bruno Tonioli about two minutes before he decided he simply had to get out of his TV clobber Credit: Rex 6 Bruno during his time as a judge on Strictly Come Dancing I was there, in this oven-cum-caravan, to interview him about his transatlantic life as a judge on both shows in the same week. I had only met him about two minutes before he decided he simply had to get out of his TV clobber. Then suddenly there he was, mere feet away from me wearing nothing but a pair of tighty whities and a very expensive-looking gold chain. He was gesticulating wildly by now and, in between puffs on a cigarette, was tearing into then Strictly pro Anton Du Beke who had been caught out calling Laila Rouass the P-word. “You say that to me and I’m gonna punch you in the f***ing face,” he boomed. Strong stuff. A bit too strong for his BBC paymasters, who asked me to exclude it from my subsequent interview for this newspaper. I would say I am very hard to shock but he had made me feel awkward during his rant about how his fellow Strictly star had made someone else feel awkward (and worse). The irony seemed completely lost on Bruno, who has famously stripped off for the cameras on many occasions. Most read in News TV HUGE SCOOP Scots dad wins £27k on Deal or No Deal as 'mystic' son stops him getting 10p HOT PLAY Watch the moment Loose Women's talkathon is gatecrashed by famous rockstar IT'S BACK! Hugely popular Amazon Prime thriller's second series date confirmed DUTY CALLS Line of Duty's Martin Compston stars in new role worlds away from BBC cop drama Common thread You say that to me and I’m gonna punch you in the f***ing face Bruno Tonioli tearing into Anton Du Beke Yet I made no fuss because it was by no means threatening and only mildly uncomfortable. Also, I had an interview to do and, well, I quite liked Bruno and he was giving me some good copy (most of which the Beeb would not later request to be ignored). Fury as BBC had complaints about Gregg Wallace’s ‘sexual remarks’ on Strictly 10yrs ago but was allowed to stay on show And, well, some stars are just a bit bonkers, aren’t they? But I couldn’t help thinking later, back at my hotel, would he have done that if I was a woman? I was reminded of that episode this week when the Gregg Wallace scandal blew up again. Not that Bruno’s behaviour was anything like that which Gregg is being accused of. But I would argue there is a common thread. Here was a star doing as he pleased without much of an apparent thought for whoever else was in the vicinity. 6 The Gregg Wallace saga goes much deeper than Gregg, his potty mouth and allegedly wandering hands Credit: BBC It is behaviour that smacks of a supreme sense of entitlement where the star is the only person who matters. It is behaviour that smacks of a supreme sense of entitlement where the star is the only person who matters Much of this attitude comes from the “talent” — a word now banned by BBC chief Tim Davie to describe those “front of camera”. Many believe they are God’s gift to whatever line of work it is that has propelled them on to the flat screen 55-incher on your wall. Confidence is a prerequisite of fame. Sharp elbows will get you the audition, only then will talent get you the gig. Bad behaviour But while celebrities and their egos are the frontmen and women of TV shows, it is the production teams that get them on the air. And unfortunately television is full of enablers — nervous executives and producers who will tolerate almost anything to get the show out. When it’s a hit they care even less how badly their stars might behave. Don’t mess with success! Indeed, the industry is awash with bad behaviour from famous faces and anyone (honest) who works in it will tell you that pretty much every star they work with can behave like a complete **** (and it’s usually the full-strength Anglo-Saxon term used). I can attest to this. In my many years of covering TV I met and wrote about the biggest names on the box on a regular basis and they all had their moments. Yes, even the saintly Ant and Dec. Just ask Kelly Brook, who blamed them for her sacking as a judge on Britain’s Got Talent in 2012. So the Gregg Wallace saga goes much deeper than Gregg Wallace, his potty mouth and allegedly wandering hands. It goes much deeper than the BBC and its patently piss-poor complaints procedure. It is about how the entire industry behaves. How time after time it has been shown to foster a toxic environment where stars are considered just too important to sack, no matter how appalling their behaviour. And it will continue to be that way until the people who perpetuate it decide enough is enough and enact the changes that are so urgently needed. They? We won’t forget them Emma 6 Emma Corrin out at a premiere of a new horror film EMMA “don’t call me a woman” Corrin has been doing her, sorry “their”, bit for gender diversity this week by appearing at the premiere of a new horror film with a brace of presumably non-female breasts, proudly on display. The star, who plays a female character in the film, showcased the daring braless look on the blood-red carpet for the remake of the classic 1922 Dracula-inspired Nosferatu. Vainglorious Emma insists on being called “they”, in keeping with the pronoun demands of her fellow non-binaries. Well, we certainly won’t forget them. Price to pay at BBC 6 BBC presenter Clive Myrie failed to disclose extra-curricular activities totalling up to £250,000 Credit: Getty NEWSREADER, Mastermind host and one of the only male stars left at the Beeb who hasn’t been revealed to be a sex pest, Clive Myrie has got himself into a pickle. He apologised this week after confessing that due to “administrative issues” he had failed to disclose extra-curricular activities totalling up to £250,000 . Strict BBC rules insist that people like Clive, who are supposed to be impartial, declare what they are up to elsewhere. Clive says he now won’t take on any other extra stuff for the time being and will instead struggle by on the £310,000 a year he gets from our licence fees (u ok hun?). But this whole episode reveals a fundamental flaw at the heart of the BBC’s argument as to why it must pay so much. The corporation says it is because of what the commercial sector offers. So it pays “market price”, despite insisting it rarely does pay that. But once installed at the BBC, stars like Clive can trade on that to make even more cash in the commercial market. So simply by having a job at the BBC, their stock rises. That would also be the case if we paid them less. Maybe if we did, executives could stop claiming to be skint – and then stop jacking up the increasingly unjustifiable licence fee. SPOTIFY’S Unwrapped week is upon us, when folk with the audio streaming app take to social media to boast about how cool their music choices are. Unless you’re a parent of young kids. Unwrapped collates all your most-played songs to reveal a bespoke top five. So my No1 was not one of the cool new indie bands I’ve been streaming all year but a song by Taylor Swift. Now I happen to like this particular tune but not as much as my daughter, who insists on it being streamed in the car from my Spotify account at least five times a journey. But it could be worse. A friend with younger kids revealed her number one was Wheels On The Bus. Cool points for that one: Zero. Ad ban a waist of time 6 A TV junk food ban will be a waste of time, the number of junk food influencers – aka snackfluencers – is expanding faster than their viewers’ waistlines Credit: instagram/elburritomonster A HARD-and-fast rule of any new public policy is that by the time it’s actually ready to be implemented, it will be completely outdated. Take the plan to ban “junk food” ads before 9pm on telly or in paid online adverts . We’ve heard about this since cavemen created their first brontosaurus smash burger. And still it won’t come in until October 2025. But even if it was introduced now it would a waste of time, as a cursory glance at social media will confirm. The number of junk food influencers – aka snackfluencers – is expanding faster than their viewers’ waistlines. Food porn accounts Only Scrans and El Burrito Monster already have a million followers. Instagram and TikTok are stuffed to the gills with six-patty burgers deep fried in cheese. Or my favourite, a burrito made of about ten items from McDonald’s. Once again, the internet charges ahead while government puffs and pants behind it like someone from My 600lb Life. No fan of Jim MANCHESTER United ’s new boss, Jim “local lad” Ratcliffe , has decided to endear himself to fans by ripping us off at the turnstiles. Ratcliffe – net worth £12.5billion – has whacked up ticket prices and scrapped all concessions so my lad’s £20 ticket is now £66. Squeezing more cash out of already fed-up Reds is quite the PR masterstroke, as the huge protests outside Old Trafford at Sunday’s Everton game showed. Now, Unlucky Jim is being spoken of with the same disdain fans have for owners the Glazers. Read more on the Scottish Sun DARR-ARGH! Weather maps reveal exact date Storm Darragh to hit Scots with rain, wind & SNOW 'SICK BEYOND BELIEF' Cops probe footage 'showing Scots woman having sex with XL Bully dog' But at least he can console himself that he now has his very own terrace chant, to the tune of The Beach Boys’ Sloop John B. All together now: “Jim Ratcliffe’s a c***, Jim Ratcliffe’s a c***, just like the Glazers . . . Jim Ratcliffe’s a c***.”
ans declare should sue after a headline uploaded to Snapchat suggests the star is going to quit the WNBA after one year, as fans grow tired of the headlines around her. One of the most popular and controversial players in women's basketball, the 22-year-old is often in the news but now fans believe the boundary of acceptability has been crossed and thus she should make a stand for herself after the latest episode. This time, the headline suggests she will quit the WNBA "again", but the catch is that she never quit it to begin with meaning that this is misinformation at best and disinformation at worst and aims to use her image to collect clicks. The outcome is that fans are left incensed and have taken to X.com, formerly Twitter, to voice their frustrations as they say the problem spans multiple social media platforms and not just Snapchat. One user wrote, "I'm sick of it!! It's time to sue!!" A second added, "It's getting out of hand honestly." Whilst a third said, "Can't even search her name on YouTube it's so bad." And a fourth concluded, "Disgusting, You Tube is bad as well! As a fan I just keep reporting everything that I can!" Reese delivers message to critics despite being so confidently outspoken, is yet to comment on the matter but she did recently take up issue with her critics after she attended an NBA game during her winter break as she watched the Boston Celtics take on the Orlando Magic. The youngster backed the Magic for the win, through their association with who is her mentor, and she wasn't disappointed as the scarcely-manned Floridian side won 1-8-104 at the Kia Center. then took the chance to hit out at some of her haters online by rhetorically and sarcastically asking, "What's my record now???" She will next take to the WNBA court on May 17 when she takes on to kick off the 2025 season. The Sky look to improve on their .325 record (13 wins) from the previous year.The IrishMinistry of Foreign Affairs has expressed condolences to Azerbaijanover the crash of the Embraer 190 passenger plane on December 25, reports. "We were saddened to hear of the tragic crash of the AzerbaijaniAirlines plane in Kazakhstan. We extend our sincere condolences toall those who have lost loved ones. Our thoughts are with thefamilies and friends of the victims," the Irish Ministry ofForeign Affairs wrote on its page on X. To note, AZAL's Embraer 190 passenger plane on the Baku-Groznyroute crashed 3 km away from Aktau airport on December 25. A total of 67 people (62 passengers and 5 crew members) were onboard the Embraer 190 airplane, flying Baku-Grozny, which crashedin Aktau. Following the crash of the passenger airplane near Aktau, 27people were hospitalized. Of them, 15 people are citizens of theRepublic of Azerbaijan, 8 of the Russian Federation, and 3 of theKyrgyz Republic. The identity of one person has not beenestablished yet. Of the victims hospitalized, 11 are being treated in theintensive care unit, 13 in the traumatology department, 2 in theneurosurgery department, and 1 in the surgical department. Thesepersons are under the control of professional doctors fromKazakhstan and those expelled from Azerbaijan and Russia. They wereprovided with prompt and specialized medical and psychologicaltreatment. Both crew pilots as well as the flight stewardess were lost, buttwo crew members survived. December 26 has been declared a day of mourning inAzerbaijan.Frequency Electronics, Inc. Announces Second Quarter and Fiscal Year 2025 Financial Results
"Antivirals are most effective when administered early in the course of an infection and tend to demonstrate the greatest benefit in patients with more severe disease. The STOMP results are not unexpected as the study design was similar to the PALM007 study except it was in patients with mild to moderate clade II mpox compared to patients with clade I mpox. It is important to note that approximately 75% of mpox patients in the randomized arms of the STOMP trial received tecovirimat more than five days after symptom onset, and higher risk patients were included in an open-label arm,” stated Diem Nguyen, Chief Executive Officer. Tecovirimat, also known as TPOXX, was developed in partnership with the U.S. Government and approved by the U.S. Food and Drug Administration to treat smallpox-a virus closely related to, but far more serious than, mpox. TPOXX was approved in 2018 based on data from 12 clinical trials of oral TPOXX in 700 healthy human volunteers, which showed no drug-related serious adverse events. Four pivotal trials in non-human primates (NHPs) and two pivotal trials in rabbits demonstrated that TPOXX significantly reduced both mortality and viral load in NHP infected with mpox virus and in rabbits infected with rabbitpox virus. The results of the animal efficacy studies were published in the July 5, 2018 issue of the New England Journal of Medicine . "Tecovirimat's mechanism of action is driven by halting viral transmission. Once virus is present in the system, the body's natural immune system plays a central role in clearing it, typically within two to four weeks in immune competent patients. Research results thus far indicate that early treatment with tecovirimat including post-exposure prophylaxis and treatment in severe cases may offer the greatest potential for patient benefit,” stated Dennis Hruby, Chief Scientific Officer. Additionally, in this study, tecovirimat exhibited a safety profile comparable to placebo. These safety results are consistent with prior studies and further support the strong safety profile that has been observed with tecovirimat over the past 15 years. Dr. Nguyen continued, "We thank our partners, the National Institute of Allergy and Infectious Diseases (NIAID) and the National Institutes of Health (NIH), the patients who participated in this trial, and the investigators who supported this trial. Their unwavering dedication to public health has been instrumental in advancing our understanding of mpox and tecovirimat.” Three randomized clinical trials, UNITY (Switzerland, Brazil, Argentina), Platinum-CAN (Canada), and EPOXI (EU), are enrolling mpox patients. Given the STOMP and PALM007 results and the design similarities across these mpox trials, the Company believes these ongoing trials are likely to yield similar results. About the STOMP Clinical Trial in Mpox The STOMP study is a randomized, placebo-controlled, double-blind study to evaluate the safety and efficacy of tecovirimat for the treatment of people with laboratory-confirmed or presumptive mpox disease. Beginning in September 2022, the study enrolled participants with mpox from Argentina, Brazil, Japan, Mexico, Peru, Thailand, and the United States, including Puerto Rico, who had symptoms for less than 14 days. Participants were randomly (2:1) assigned to receive tecovirimat or a placebo for 14 days. The number of capsules and frequency of dosage were based on patient weight. Participants with severe disease, certain skin conditions, or significantly suppressed immune systems received open-label tecovirimat rather than being randomized. The study monitored participants' safety across randomized and open label arms. In the randomized arms, STOMP examined the time to full mpox lesion resolution, viral clearance, and study participants' reports of pain. Participants were followed for 28 days with a study site visit at day 29 and then again at day 57 for possible recrudescence of infection. About SIGA SIGA Technologies (SIGA) (NASDAQ: SIGA) is a commercial-stage pharmaceutical company and leader in global health focused on the development of innovative medicines to treat and prevent infectious diseases. With a primary focus on orthopoxviruses, we are dedicated to protecting humanity against the world's most severe infectious diseases, including those that occur naturally, accidentally, or intentionally. Through partnerships with governments and public health agencies, we work to build a healthier and safer world by providing essential countermeasures against these global health threats. Our flagship product, TPOXX® (tecovirimat), is an antiviral medicine approved in the U.S. and Canada for the treatment of smallpox and authorized in Europe and the UK for the treatment of smallpox, mpox (monkeypox), cowpox, and vaccinia complications. For more information about SIGA, visit www.siga.com . Forward-Looking Statements This press release contains "forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995, as amended, including statements relating to the efficacy of tecovirimat to treat mpox in certain patient populations and the results of ongoing mpox clinical studies. Forward-looking statements include statements regarding our future financial position, business strategy, budgets, projected costs, plans and objectives of management for future operations. The words "may,” "continue,” "estimate,” "intend,” "plan,” "will,” "believe,” "project,” "expect,” "seek,” "anticipate,” "could,” "should,” "target,” "goal,” "potential” and similar expressions may identify forward-looking statements, but the absence of these words does not necessarily mean that a statement is not forward-looking. Such forward-looking statements are subject to various known and unknown risks and uncertainties, and SIGA cautions you that any forward-looking information provided by or on behalf of SIGA is not a guarantee of future performance. SIGA's actual results could differ materially from those anticipated by such forward-looking statements due to a number of factors, some of which are beyond SIGA's control, including, but not limited to, (i) the risk that BARDA elects, in its sole discretion as permitted under the 75A50118C00019 BARDA Contract (the "BARDA Contract”), not to exercise the remaining unexercised option under the BARDA Contract, (ii) the risk that SIGA may not complete performance under the BARDA Contract on schedule or in accordance with contractual terms, (iii) the risk that the BARDA Contract or U.S. Department of Defense contracts are modified or canceled at the request or requirement of, or SIGA is not able to enter into new contracts to supply TPOXX to, the U.S. Government, (iv) the risk that the nascent international biodefense market does not develop to a degree that allows SIGA to continue to successfully market TPOXX internationally, (v) the risk that potential products, including potential alternative uses or formulations of TPOXX that appear promising to SIGA or its collaborators, cannot be shown to be efficacious or safe in subsequent pre-clinical or clinical trials, (vi) the risk that target timing for deliveries of product to customers, and the recognition of related revenues, are delayed or adversely impacted by the actions, or inaction, of contract manufacturing organizations, or other vendors, within the supply chain, or due to coordination activities between the customer and supply chain vendors, (vii) the risk that SIGA or its collaborators will not obtain appropriate or necessary governmental approvals to market these or other potential products or uses, (viii) the risk that SIGA may not be able to secure or enforce sufficient legal rights in its products, including intellectual property protection, (ix) the risk that any challenge to SIGA's patent and other property rights, if adversely determined, could affect SIGA's business and, even if determined favorably, could be costly, (x) the risk that regulatory requirements applicable to SIGA's products may result in the need for further or additional testing or documentation that will delay or prevent SIGA from seeking or obtaining needed approvals to market these products, (xi) the risk that the volatile and competitive nature of the biotechnology industry may hamper SIGA's efforts to develop or market its products, (xii) the risk that changes in domestic or foreign economic and market conditions may affect SIGA's ability to advance its research or may affect its products adversely, (xiii) the effect of federal, state, and foreign regulation, including drug regulation and international trade regulation, on SIGA's businesses, (xiv) the risk of disruptions to SIGA's supply chain for the manufacture of TPOXX®, causing delays in SIGA's research and development activities, causing delays or the re-allocation of funding in connection with SIGA's government contracts, or diverting the attention of government staff overseeing SIGA's government contracts, (xv) risks associated with actions or uncertainties surrounding the debt ceiling, (xvi) the risk that the U.S. or foreign governments' responses (including inaction) to national or global economic conditions or infectious diseases, are ineffective and may adversely affect SIGA's business, and (xvii) risks associated with responding to an mpox outbreak, as well as the risks and uncertainties included in Item 1A "Risk Factors” of our Annual Report on Form 10-K for the year ended December 31, 2023 and SIGA's subsequent filings with the Securities and Exchange Commission. SIGA urges investors and security holders to read those documents free of charge at the SEC's website at http://www.sec.gov . All such forward-looking statements are current only as of the date on which such statements were made. SIGA does not undertake any obligation to update publicly any forward-looking statement to reflect events or circumstances after the date on which any such statement is made or to reflect the occurrence of unanticipated events.
TikTok's future in the U.S. appeared uncertain on Friday after a federal appeals court rejected a legal challenge to a law that requires the social media platform to cut ties with its China-based parent company or be banned by mid-January. A panel of three judges on The U.S. Court of Appeals for the District of Columbia Circuit ruled unanimously that the law withstood constitutional scrutiny, rebuffing arguments from the two companies that the statute violated their rights and the rights of TikTok users in the U.S. The government has said it wants ByteDance to divest its stakes in TikTok. But if it doesn't and the platform goes away, it would have a seismic impact on the lives of content creators who rely on the platform for income as well as users who use it for entertainment and connection. Here are some details on the ruling and what could happen next: What does the ruling say? In their lawsuit, TikTok and ByteDance, which is also a plaintiff in the case, had challenged the law on various fronts, arguing in part that the statute ran afoul of the First Amendment and was an unconstitutional bill of attainder that unfairly targeted the two companies. But the court sided with attorneys for the Justice Department who said that the government was attempting to address national security concerns and the way in which it chose to do so did not violate the constitution. The Justice Department has argued in court that TikTok poses a national security risk due to its connections to China. Officials say that Chinese authorities can compel ByteDance to hand over information on TikTok's U.S. patrons or use the platform to spread, or suppress, information. However, the U.S. hasn't publicly provided examples of that happening. The appeals court ruling, written by Judge Douglas Ginsburg, said the law was “carefully crafted to deal only with control by a foreign adversary." The judges also rejected the claim that the statute was an unlawful bill of attainder or a taking of property in violation of the Fifth Amendment. Furthermore, Ginsburg wrote the law did not violate the First Amendment because the government is not looking to “suppress content or require a certain mix of content” on TikTok. What happens next? TikTok and ByteDance are expected to appeal the case to the Supreme Court, but it's unclear whether the court will take up the case. TikTok indicated in a statement on Friday the two companies are preparing to take their case to high court, saying the Supreme Court has “an established historical record of protecting Americans’ right to free speech." "We expect they will do just that on this important constitutional issue,” a company spokesperson said. Alan Morrison, a professor at The George Washington University Law School, said he expects the Supreme Court to take up the case because of the novelty of the issues raised in the lawsuit. If that happens, attorneys for the two companies still have to convince the court to grant them an emergency stay that will prevent the government from enforcing the Jan. 19 divestiture deadline stipulated in the law, Morrison said. Such a move could drag out the process until the Justices make a ruling. Tiffany Cianci, a TikTok content creator who has supported the platform, said she was not shocked about the outcome of the court's ruling on Friday because lower courts typically defer to the executive branch on these types of cases. She believes the company will have a stronger case at the Supreme Court. “I believe that the next stages are more likely to produce a victory for TikTokers and for TikTok as a whole,” Cianci said. What about Trump? Another wild card is President-elect Donald Trump, who tried to ban TikTok during his first term but said during the recent presidential campaign that he is now against such action . The Trump transition team has not offered details on how Trump plans to carry out his pledge to “save TikTok." But spokeswoman Karoline Leavitt said in a statement last month that he plans to “deliver” on his campaign promises. After Trump takes office on Jan. 20th, it would fall on his Justice Department to enforce the law and punish any potential violators. Penalties would apply to any app stores that would violate a prohibition on TikTok and to internet hosting services which would be barred from supporting it. Some have speculated that Trump could ask his Justice Department to abstain from enforcing the law. But tech companies like Apple and Google, which offer TikTok's app on their app stores, would then have to trust that the administration would not come after them for any violations. Craig Singleton, senior director of the China program at the Foundation for Defense of Democracies, said enforcement discretion — or executive orders — can not override existing law, leaving Trump with “limited room for unilateral action." There are other things Trump could potentially do. It's possible he could invoke provisions of the law that allow the president to determine whether a sale or a similar transaction frees TikTok from “foreign adversary” control. Another option is to urge Congress to repeal the law. But that too would require support from congressional Republicans who have overwhelmingly supported the prospect of getting TikTok out of the hands of a Chinese company. In a statement issued Friday, Republican Rep. John Moolenaar of Michigan, chairman of the House Select Committee on China, said he was “optimistic that President Trump will facilitate an American takeover of TikTok” and allow its continued use in the United States. Is anyone trying to buy TikTok? ByteDance has said it won't sell TikTok . And even if it wanted to, a sale of the proprietary algorithm that powers TikTok is likely to get blocked under Chinese export controls that the country issued in 2020. That means if TikTok is sold without the algorithm, its likely that the buyer would only purchase a shell of the platform that doesn't contain the technology that made the app a cultural powerhouse. Still, some investors, including Trump’s former Treasury Secretary Steven Mnuchin and billionaire Frank McCourt, have expressed interest in buying it. This week, a spokesperson for McCourt’s Project Liberty initiative, which aims to protect online privacy, said participants in their bid have made informal commitments of more than $20 billion in capital. The spokesperson did not disclose the identity of the participants. Haleluya Hadero, The Associated Press
New York Rangers goaltender Igor Shesterkin agreed to a record-setting eight-year, $92 million contract on Friday, according to multiple reports. Shesterkin's deal, which averages $11.5 million annually and runs through the 2032-33 season, is the largest ever for a goaltender. The previous high was an eight-year, $84 million deal ($10.5 million average) that Carey Price signed with the Montreal Canadiens in 2017. Shesterkin, who won the Vezina Trophy as the top netminder for the 2021-22 season, turned down an eight-year, $88 million offer just prior to the start of this season. He is making $5.66 million in 2023-24 in the final season of a four-year, $22.67 million contract. The Moscow native finished third in Hart Trophy (MVP) balloting during his stellar 2021-22 season in when he went 36-13-4 and led the NHL with both a 2.07 goals-against average and .935 save percentage. Shesterkin, who turns 29 on Dec. 30, has won 36 or more games in each of the past three regular seasons. But this season, he is just 8-9-1 with a personal-worst 3.05 GAA in 18 games this season. His .908 save percentage is also his worst. Overall, Shesterkin is 143-68-18 with a 2.48 GAA and .920 save percentage in 231 appearances (226 starts) over six seasons. In the postseason, he is 23-20-0 with a 2.41 GAA and .928 save percentage. Reports of the deal began circulating shortly after the Rangers traded captain Jacob Trouba to the Anaheim Ducks. That freed up money for next season as Trouba was in the sixth season of a seven-year, $56 million deal. --Field Level MediaVikings cornerback Stephon Gilmore out vs. the Falcons; six players questionableInsight Acquisition Corp Stockholders Approve Extension of Business Combination Period Through ...
Published 5:22 pm Friday, December 27, 2024 By Data Skrive The Oklahoma City Thunder against the Charlotte Hornets is one game in particular to catch on a Saturday NBA schedule that features nine thrilling matchups. We have everything you need in terms of how to watch today’s NBA action right here. Take a look at the links below. Sign up for NBA League Pass to get access to games, live and on-demand, and more for the entire season and offseason. Watch ESPN originals, The Last Dance and more NBA content on ESPN+. Use our link to sign up for ESPN+ or the Disney bundle. Not all offers available in all states, please visit BetMGM for the latest promotions for your area. Must be 21+ to gamble, please wager responsibly. If you or someone you know has a gambling problem, contact 1-800-GAMBLER .
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