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Why tech giants such as Microsoft, Amazon, Google and Meta are betting big on nuclear powerMichael Croley | (TNS) Bloomberg News In the old days of 2016, when golfers visited the Dormie Club in West End, North Carolina — 15 minutes from the hotbed of American golf, Pinehurst — they were greeted by a small, single-wide trailer and a rugged pine straw parking lot. Related Articles Travel | A preview of some stunning hotels and resorts opening in 2025 Travel | Travel scams that can hurt your credit or finances Travel | Travel: Paddle the Loxahatchee River, one of two National Wild and Scenic Rivers in Florida Travel | 7 family-friendly ski resorts in the US that won’t break the bank Travel | Friday expected to be among busiest holiday travel days at BWI Marshall Airport That trailer is now long gone. A gate has been installed at the club’s entrance and a long driveway leads to a grand turnaround that sweeps you past a new modern clubhouse that’s all right angles, with floor-to-ceiling glass. Seconds after you exit your car, valets are zipping up in golf carts, taking your name, then your bags, handing you keys to your own golf cart, and then zipping off to drop your luggage in the four-bedroom cottage where you’ll stay. A short walk past an expansive putting green you’ll find the pro shop — and then you’ll see the club’s most elegant feature: its golf course. The changes have all come about because Dormie Club was acquired in 2017 by the Dormie Network, a national group that owns seven private golf facilities from Nebraska to New Jersey. (“Dormie” is a word for being ahead in golf — the names were coincidences.) A key to the network’s success has been its ability to find clubs ripe for acquisition, with outstanding golf courses and existing on-site lodging or the room to build it, says Zach Peed, president of the company and its driving force. After investing in Arbor Links Golf Club in Nebraska City, Nebraska, in late 2015, Peed believed he saw an opening in the golf market: a new model of hospitality for traveling professionals who wanted a pure golf experience that eschewed the pools and pickleball courts of their home clubs. His clubs would become dream golf-only getaways for avid players and their pals. “Dormie Network’s concept was sparked by having played competitive golf in college, combined with an element of experiencing and understanding hospitality,” says Peed. “It made sense to blend the two to create golf trips that had more value than just playing golf. We want genuine hospitality to help create unforgettable memories and new friendships.” Part of that formula has been in the lodging strategy; in North Carolina, 15 four-bedroom cottages now are a short golf cart ride from the main clubhouse. In each, golfers all have their own king-size bed and en suite bathroom. A large common room is dominated by a flatscreen television along with a well-stocked bar and snacks. That ability to be both social, or tucked away in your room, extends to the expansive new clubhouse, where a high-ceilinged bar area with blond wood creates an inviting space for dining and drinking, and several hideaway rooms allow for more private diners with just your group. So far, their commitment to hospitality has been helping them expand in both membership and club usage in the increasingly competitive market for traveling golfers. Major players such as Bandon Dunes, Pinehurst Resort, and the Cabot Collection have created — or renovated — a new paradigm where golfers get dining and lodging that’s as showcase-worthy as the courses they play. Comfortable sheets and options beyond pub food aren’t luxuries anymore, but staples for many group trips. Dormie has answered that call by focusing on both the big details and the small ones, like having the dew wiped off each golf cart at dawn outside guest cottages before the day begins or having a tray of cocktails delivered to golfers as their final putt falls on the 18th green. These touches may seem over-the-top, but they stand out in a world where golf travel is increasingly popular — and expensive — after the pandemic lockdowns. Since 2020 there has been an explosion in participation in the sport, with new golfers picking up the game and avid golfers playing more: According to the National Golf Foundation, a record 531 million rounds were played in 2023, surpassing the high of 529 million set in 2021. Supreme Golf, a public golf booking website, reports in its latest analysis that the average cost of a tee time has increased to $49 in 2024 from $38 in 2019, a 30% increase. Those cost increases are also on par (pun intended) with the costs of private clubs and initiation fees during that same period, where membership rosters that were dwindling pre-COVID now have waitlists 50 to 60 people deep, according to Jason Becker, co-founder and chief executive officer of Golf Life Navigators, which matches homebuyers with golf course communities. “There’s been an absolute run on private golf. If we use southwest Florida as an example, where there are 158 golf communities, this time last November, only five had memberships available,” he said. That inability to find a club close to home has pushed avid golfers to look farther afield, choosing national memberships at clubs that require traveling, usually via plane, to play. Dormie has capitalized on this growing segment, offering two types of memberships: First, a national membership, where members pay an initiation fee and monthly dues just as they would at a local club, but instead of one club they have access to seven. The second option is a signature membership for companies, “which allows businesses to use our properties for entertainment needs and requires a multiyear commitment,” Peed says. The network also offers a limited number of regional memberships for those living within a certain distance of one of its clubs. Dormie Network declined to provide the cost of memberships or monthly dues and wouldn’t give membership numbers, but the clubs are structured to lodge roughly 60 golfers, max, on-site at any given property at any time. The total number of beds across the network’s portfolio of properties has increased from 84 in 2019 to 432 today. It saw a jump from 10,000 room nights in 2019 to 48,000 in 2023. This September, Dormie opened GrayBull in Maxwell, in Nebraska’s, Sandhills region. Dormie Network tabbed David McLay Kidd to build the course, who also built the original course at Oregon’s famed Bandon Dunes. Kidd says of the property GrayBull sits on, “It’s like the Goldilocks thing: not too flat, not too steep. It’s kind of in a bowl that looks inwards, and there are no bad views.” That kind of remote destination, where the long-range views are only Mother Nature or other golf holes, is what drives many traveling golfers these days. Peed says his team leaned on years of knowledge from Dormie’s acquisitions as they built GrayBull, which started construction in 2022. “We had an understanding of how our members and guests use the clubs that allowed us to take a blank canvas in the Sandhills of Nebraska and combine all of the greatest aspects of each Dormie property into one.” ©2024 Bloomberg L.P. Visit bloomberg.com. Distributed by Tribune Content Agency, LLC.
NEW YORK (AP) — Yankees slugger Aaron Judge wins his second AL MVP award after leading MLB with 58 home runs.Schwarzenegger wore 'McFelon' T-shirt mocking Trump? No, image is altered | Fact checkQ3 2024 Overview SAN DIEGO , Dec. 5, 2024 /PRNewswire/ -- Petco Health and Wellness Company, Inc. (Nasdaq: WOOF), a complete partner in pet health and wellness, today announced its third quarter 2024 financial results. In the third quarter of 2024, Petco delivered net revenue of $1.51 billion , up 1.2 percent versus prior year. On an as-reported basis, the company's consumables business was up 2.7 percent versus prior year, and services and other business was up 5.0 percent versus prior year. Growth in the company's consumables and services and other businesses was offset by the company's supplies and companion animal business, down 2.8 percent versus prior year. GAAP net loss in the third quarter of 2024 was $16.7 million , or $(0.06) per share, compared to GAAP net loss of $1.2 billion , or $(4.63) per share in the prior year, which included a $1.2 billion non-cash goodwill impairment charge associated with goodwill originally recorded in 2015. Adjusted Net Income 1 was $(6.5) million , or $(0.02) per share 1 , compared to $(14.5) million , or $(0.05) per share 1 in the prior year. Adjusted EBITDA 1 was $81.2 million compared to $72.2 million in the prior year. "Our third quarter results demonstrate the meaningful progress we're making to strengthen our retail fundamentals to drive sustainable, profitable growth," said Joel Anderson , Petco's Chief Executive Officer. "While there is more work to do, our improving results increase our conviction that we are on the right path to position Petco to win long-term. Our entire organization is focused on driving profitability and free cash flow, and I'm confident we're set up for a solid finish to 2024." (1) Adjusted EBITDA, Adjusted Net Income, Adjusted Earnings Per Share ("Adjusted EPS"), and Free Cash Flow are non-GAAP financial measures. See "Non-GAAP Financial Measures" for additional information on non-GAAP financial measures and a reconciliation to the most comparable GAAP measures. Fiscal Q4 2024 Outlook The company is providing Q4 guidance for revenue, Adjusted EBITDA, and Adjusted EPS, in addition to full year interest expense and capital expenditure expectations. For Fiscal Q4 2024, the company expects: Metric* FQ4 2024 Guidance Net Revenue ~ $1.55 billion Adjusted EBITDA Between $90 million and $95 million, including a minimum of $10 million in third party consulting fees associated with our transformation effort Adjusted EPS Between $0.00 and $0.02 For Fiscal 2024 (a 52-week year), the company expects the following: Metric* 2024 Guidance, YoY Net interest expense ~$140 million Capital Expenditures ~$130 million *Assumptions in the guidance include that economic conditions, currency rates and the tax and regulatory landscape remain generally consistent. For fiscal 2024, our guidance anticipates a 26 percent tax rate, and 273 million weighted average diluted share count. Adjusted EBITDA and Adjusted EPS are non-GAAP financial measures and have not been reconciled to the most comparable GAAP outlook because it is not possible to do so without unreasonable efforts due to the uncertainty and potential variability of reconciling items, which are dependent on future events and often outside of management's control and which could be significant. Because such items cannot be reasonably predicted with the level of precision required, we are unable to provide outlook for the comparable GAAP measures. Forward-looking estimates of Adjusted EBITDA and Adjusted EPS are made in a manner consistent with the relevant definitions and assumptions noted herein and in our filings with the Securities and Exchange Commission. Earnings Conference Call Webcast Information: Management will host an earnings conference call on December 5, 2024 at approximately 4:30 PM Eastern Time to discuss the company's financial results. The conference call will be accessible through a live webcast. Interested investors and other individuals can access the webcast, earnings release, and earnings presentation via the company's investor relations page at ir.petco.com . A replay of the webcast will be archived on the company's investor relations page through December 19, 2024 until approximately 5:00 PM Eastern Time . About Petco, The Health + Wellness Co.: Founded in 1965, Petco is a category-defining health and wellness company focused on improving the lives of pets, pet parents and our own Petco partners. We've consistently set new standards in pet care while delivering comprehensive pet wellness products, services and solutions, and creating communities that deepen the pet-pet parent bond. We operate more than 1,500 pet care centers across the U.S., Mexico and Puerto Rico , which offer merchandise, companion animals, grooming, training and a growing network of on-site veterinary hospitals and mobile veterinary clinics. Our complete pet health and wellness ecosystem is accessible through our pet care centers and digitally at petco.com and on the Petco app . In tandem with Petco Love , a life-changing independent nonprofit organization, we work with and support thousands of local animal welfare groups across the country and, through in-store adoption events, we've helped find homes for nearly 7 million animals. Forward-Looking Statements: This earnings release contains "forward-looking statements" within the meaning of the Private Securities Litigation Reform Act of 1995 as contained in Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, concerning expectations, beliefs, plans, objectives, goals, strategies, future events or performance and underlying assumptions and other statements that are not statements of historical fact, including, but not limited to, statements regarding our Q4 and full year 2024 guidance, operational reset of our business, our competitive positioning, profitability, cost action plans and associated cost-savings. Such forward-looking statements can generally be identified by the use of forward-looking terms such as "believes," "expects," "may," "intends," "will," "shall," "should," "anticipates," "opportunity," "illustrative," or the negative thereof or other variations thereon or comparable terminology. Although Petco believes that the expectations and assumptions reflected in these statements are reasonable, there can be no assurance that these expectations will prove to be correct or that any forward-looking results will occur or be realized. Nothing contained in this earnings release is, or should be relied upon as, a promise or representation or warranty as to any future matter, including any matter in respect of the operations or business or financial condition of Petco. All forward-looking statements are based on current expectations and assumptions about future events that may or may not be correct or necessarily take place and that are by their nature subject to significant uncertainties and contingencies, many of which are outside the control of Petco. Forward-looking statements are subject to a number of risks, uncertainties and other factors that could cause actual results or events to differ materially from the potential results or events discussed in the forward-looking statements, including, without limitation, those identified in this earnings release as well as the following: (i) increased competition (including from multi-channel retailers, mass and grocery retailers, and e-Commerce providers); (ii) reduced consumer demand for our products and/or services; (iii) our reliance on key vendors; (iv) our ability to attract and retain qualified employees; (v) risks arising from statutory, regulatory and/or legal developments; (vi) macroeconomic pressures in the markets in which we operate, including inflation, prevailing interest rates and the impact of tariffs; (vii) failure to effectively manage our costs; (viii) our reliance on our information technology systems; (ix) our ability to prevent or effectively respond to a data privacy or security breach; (x) our ability to effectively manage or integrate strategic ventures, alliances or acquisitions and realize the anticipated benefits of such transactions; (xi) economic or regulatory developments that might affect our ability to provide attractive promotional financing; (xii) business interruptions and other supply chain issues; (xiii) catastrophic events, political tensions, conflicts and wars (such as the ongoing conflicts in Ukraine and the Middle East ), health crises, and pandemics; (xiv) our ability to maintain positive brand perception and recognition; (xv) product safety and quality concerns; (xvi) changes to labor or employment laws or regulations; (xvii) our ability to effectively manage our real estate portfolio; (xviii) constraints in the capital markets or our vendor credit terms; (xix) changes in our credit ratings; (xx) impairments of the carrying value of our goodwill and other intangible assets; (xxi) our ability to successfully implement our operational adjustments, achieve the expected benefits of our cost action plans and drive improved profitability; and (xxii) the other risks, uncertainties and other factors identified under "Risk Factors" and elsewhere in Petco's Securities and Exchange Commission filings. The occurrence of any such factors could significantly alter the results set forth in these statements. Petco cautions that the foregoing list of risks, uncertainties and other factors is not complete, and forward-looking statements speak only as of the date they are made. Petco undertakes no duty to update publicly any such forward-looking statement, whether as a result of new information, future events or otherwise, except as may be required by applicable law, regulation or other competent legal authority. PETCO HEALTH AND WELLNESS COMPANY, INC. CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS (In thousands, except per share amounts) (Unaudited and subject to reclassification) 13 Weeks Ended November 2, 2024 October 28, 2023 Percent Change Net sales: Products $ 1,263,194 $ 1,257,803 0 % Services and other 248,243 236,363 5 % Total net sales 1,511,437 1,494,166 1 % Cost of sales: Products 782,240 787,994 (1 %) Services and other 153,440 156,171 (2 %) Total cost of sales 935,680 944,165 (1 %) Gross profit 575,757 550,001 5 % Selling, general and administrative expenses 571,780 559,611 2 % Goodwill impairment — 1,222,524 (100 %) Operating income (loss) 3,977 (1,232,134) N/M Interest income (1,346) (1,139) 18 % Interest expense 35,797 36,557 (2 %) Loss on partial extinguishment of debt — 174 (100 %) Other non-operating income (8,465) (113) 7,391 % Loss before income taxes and income from equity method investees (22,009) (1,267,613) (98 %) Income tax benefit (857) (22,902) (96 %) Income from equity method investees (4,479) (3,574) 25 % Net loss attributable to Class A and B-1 common stockholders $ (16,673) $ (1,241,137) (99 %) Net loss per Class A and B-1 common share: Basic $ (0.06) $ (4.63) (99 %) Diluted $ (0.06) $ (4.63) (99 %) Weighted average shares used in computing net loss per Class A and B-1 common share: Basic 274,495 267,852 2 % Diluted 274,495 267,852 2 % PETCO HEALTH AND WELLNESS COMPANY, INC. CONSOLIDATED BALANCE SHEETS (In thousands, except per share amounts) (Unaudited and subject to reclassification) November 2, 2024 February 3, 2024 ASSETS Current assets: Cash and cash equivalents $ 116,675 $ 125,428 Receivables, less allowance for credit losses 1 40,432 44,369 Merchandise inventories, net 690,291 684,502 Prepaid expenses 46,720 58,615 Other current assets 37,665 38,830 Total current assets 931,783 951,744 Fixed assets 2,233,558 2,173,015 Less accumulated depreciation (1,493,752) (1,356,648) Fixed assets, net 739,806 816,367 Operating lease right-of-use assets 1,328,398 1,384,050 Goodwill 980,064 980,297 Trade name 1,025,000 1,025,000 Other long-term assets 206,429 205,694 Total assets $ 5,211,480 $ 5,363,152 LIABILITIES AND EQUITY Current liabilities: Accounts payable and book overdrafts $ 447,673 $ 485,131 Accrued salaries and employee benefits 129,486 101,265 Accrued expenses and other liabilities 190,789 200,278 Current portion of operating lease liabilities 340,437 310,507 Current portion of long-term debt and other lease liabilities 5,294 15,962 Total current liabilities 1,113,679 1,113,143 Senior secured credit facilities, net, excluding current portion 1,576,856 1,576,223 Operating lease liabilities, excluding current portion 1,064,322 1,116,615 Deferred taxes, net 210,708 251,629 Other long-term liabilities 123,077 121,113 Total liabilities 4,088,642 4,178,723 Commitments and contingencies Stockholders' equity: Class A common stock 2 237 231 Class B-1 common stock 3 38 38 Class B-2 common stock 4 — — Preferred stock 5 — — Additional paid-in-capital 2,271,052 2,229,582 Accumulated deficit (1,135,221) (1,047,243) Accumulated other comprehensive (loss) income (13,268) 1,821 Total stockholders' equity 1,122,838 1,184,429 Total liabilities and stockholders' equity $ 5,211,480 $ 5,363,152 (1) Allowances for credit losses are $1,623 and $1,806, respectively (2) Class A common stock, $0.001 par value: Authorized - 1.0 billion shares; Issued and outstanding - 237.2 million and 231.2 million shares, respectively (3) Class B-1 common stock, $0.001 par value: Authorized - 75.0 million shares; Issued and outstanding - 37.8 million shares (4) Class B-2 common stock, $0.000001 par value: Authorized - 75.0 million shares; Issued and outstanding - 37.8 million shares (5) Preferred stock, $0.001 par value: Authorized - 25.0 million shares; Issued and outstanding - none PETCO HEALTH AND WELLNESS COMPANY, INC. CONSOLIDATED STATEMENTS OF CASH FLOWS (In thousands) (Unaudited and subject to reclassification) 39 Weeks Ended November 2, 2024 October 28, 2023 Cash flows from operating activities: Net loss $ (87,979) $ (1,257,635) Adjustments to reconcile net loss to net cash provided by operating activities: Depreciation and amortization 149,414 148,593 Amortization of debt discounts and issuance costs 3,661 3,658 Provision for deferred taxes (35,629) (35,164) Equity-based compensation 40,705 64,431 Impairments, write-offs and losses on sale of fixed and other assets 8,449 2,202 Loss on partial extinguishment of debt — 920 Income from equity method investees (13,557) (10,032) Amounts reclassified out of accumulated other comprehensive (loss) income (3,035) 674 Goodwill impairment — 1,222,524 Non-cash operating lease costs 311,347
Noted Kannada filmmaker R Ananth Raju, known for films like Appu Pappu, Mast Maja Maadi and Nanda is all set to make his comeback with his latest film, a revenge drama titled, Capital City. The comedy-romance film directed by Ananth Raju featured Kichcha Sudeepa, Vijay Raghavendra, Diganth, Naga Kiran, Komal and Jennifer Kotwal in the lead roles. Capital City trailer and songs unveiled The trailer and songs of Capital City starring Rajeev Reddy of Ramba fame was unveiled recently. Jayanagara MLA C.K. Ramamurthy and BJP leader Renukacharya along with spiritual leaders Srimalaya Shantamuni Swamigal and Sri Aditya Swamiji of Shivagange graced the event along with prominent members of the Kannada film fraternity. Capital City is bankrolled by twenty different producers under the banner of Infinity Creations. ALSO READ: Back To School, Kannada Film Paatashaala’s Teaser Unveiled Based on Bengaluru underground The film is set against the backdrop of the Bengaluru underworld. It follows the story of a troubled hero navigating through his hardships, with action-packed sequences balanced by emotional depth. Alongside Rajeev Reddy, actress Prerana stars as the heroine and the film also features Ravi Shankar, Sharath Lohitashwa and K.S. Sridhar. Some of the producers also have cameo roles in the film. Director Ananth Raju said that preparations are underway to release the film by the end of January 2025. About the film's plot, Rajeev Reddy described it as a tale of revenge, emphasising the theme of self-protection in the face of adversity through his character. At the event, Prerana, producers Manjunath, Colonel Rajendra, Shivappa Kudlur, Antony Raj and Krishnamurthy, along with music director Nag, shared more insights into the film’s storyline and musical elements. Get Latest News Live on Times Now along with Breaking News and Top Headlines from Kannada, Entertainment News and around the world.The Pan-Niger Delta Forum has stated that the Niger Delta is the only region in Nigeria that can rightfully claim marginalisation or impoverishment. PANDEF was responding to a Thursday remark made by the Arewa Consultative Forum to President Bola Tinubu, which claimed that the economic policies of his government were impoverishing the North. However, the National Spokesman of PANDEF, Chief Christopher Ominimini, in a statement released on Saturday, stressed that oil, which is found in the Niger Delta region, is the mainstay of the nation’s economy. Yet, the people of the region have not seen corresponding development. Ominimini said that decades of oil exploration and extraction activities in the region had resulted in pollution of farmlands, rivers, and the environment, but the region has yet to see the benefits of this wealth. He expressed dismay that while the revenue from oil extracted from the Niger Delta goes to the Federal Government, revenue from other regions is kept within those regions, which he described as an injustice. The statement read: “Our resources feed the nation, while resources from other geopolitical zones, including the North, are kept for their own use and personal gain.” He continued, “The gold deposits in Northern Nigeria and other parts of the country have not been considered for the benefit of the entire country, but rather for the indigenes and top individual businesses, including foreign nationals like the Chinese and Lebanese, all for individual benefits.” “Why do other regions mine and control their resources, while the oil and gas from the Niger Delta are controlled by the Nigerian state?” Ominimini argued that this selective injustice hurts the nation’s progress, stating, “Selective injustice or justice in a nation usually backfires.” He alleged that the insurgency in Northern Nigeria was linked to the theft of solid minerals, including underground raw gold, and questioned why the government destroyed local petroleum refineries in the Niger Delta while turning a blind eye to illegal mining in the North. Related News ACF suspends chairman for criticising Tinubu’s policies Soldiers arrest 28 suspected oil thieves in N'Delta Lakurawa terror group using drones to track military, civilians — Experts PANDEF also called on the Federal Government to provide a legal framework for artisanal miners to operate. He added that this would create jobs, reduce the waste of Nigeria’s earnings, boost technological knowledge, and decrease corruption, particularly as the country continues to import refined products. Despite the oil wealth in the Niger Delta, Ominimini highlighted that the people of the region do not know how much oil and gas are extracted, as efforts to meter the oil flow stations or the export terminals have been unsuccessful. Furthermore, most of the oil block owners are from regions outside the Niger Delta, reinforcing the lopsidedness of Nigeria’s system. “The Nigerian state is wicked to the Niger Delta Region,” Ominimini said. “The rulers prefer collecting penalties from international oil companies for flaring gas rather than addressing the environmental disaster caused by gas flaring, which could be converted for domestic use and economic purposes.” He went on to say, “Our fishing and farming activities are now impossible as our ecosystem has been destroyed by oil exploitation. Our lifespan is shortened, and we bear the brunt of the oil exploitation alone.” Ominimini lamented that no one in the federal government cared about the plight of the Niger Delta people, but warned, “If things do not change, God will come to our rescue.” He also pointed out that despite the oil found in the Niger Delta, oil block owners are mostly from other regions, and there is little or no corporate social responsibility from the International Oil Companies or the federal government. The statement concluded: “Our people have been excluded from participation in the oil industry. It seems like a well-planned scheme against the people of the Niger Delta. How can the only two executive positions on the NNPCL board be occupied by Northerners? What a shame!” Ominimini also questioned those complaining about marginalisation, saying, “Where were those complaining now when they were in positions of authority?” “The only region that can truly claim marginalisation or impoverishment in Nigeria is the Niger Delta Region,” he concluded. “PANDEF believes that justice must be holistic, and the most impoverished people in Nigeria are those of the Niger Delta. This must be addressed without delay.”Unlike scores of people who scrambled for the blockbuster drugs Ozempic and Wegovy to lose weight in recent years, Danielle Griffin had no trouble getting them. The 38-year-old information technology worker from New Mexico had a prescription. Her pharmacy had the drugs in stock. And her health insurance covered all but $25 to $50 of the monthly cost. For Griffin, the hardest part of using the new drugs wasn’t access. It was finding out that the much-hyped medications didn’t really work for her. “I have been on Wegovy for a year and a half and have only lost 13 pounds,” said Griffin, who watches her diet, drinks plenty of water and exercises regularly. “I’ve done everything right with no success. It’s discouraging.” In clinical trials, most participants taking Wegovy or Mounjaro to treat obesity lost an average of 15% to 22% of their body weight — up to 50 pounds or more in many cases. But roughly 10% to 15% of patients in those trials were “nonresponders” who lost less than 5% of their body weight. Now that millions of people have used the drugs, several obesity experts told The Associated Press that perhaps 20% of patients — as many as 1 in 5 — may not respond well to the medications. It's a little-known consequence of the obesity drug boom, according to doctors who caution eager patients not to expect one-size-fits-all results. “It's all about explaining that different people have different responses,” said Dr. Fatima Cody Stanford, an obesity expert at Massachusetts General Hospital The drugs are known as GLP-1 receptor agonists because they mimic a hormone in the body known as glucagon-like peptide 1. Genetics, hormones and variability in how the brain regulates energy can all influence weight — and a person's response to the drugs, Stanford said. Medical conditions such as sleep apnea can prevent weight loss, as can certain common medications, such as antidepressants, steroids and contraceptives. “This is a disease that stems from the brain,” said Stanford. “The dysfunction may not be the same” from patient to patient. Despite such cautions, patients are often upset when they start getting the weekly injections but the numbers on the scale barely budge. “It can be devastating,” said Dr. Katherine Saunders, an obesity expert at Weill Cornell Medicine and co-founder of the obesity treatment company FlyteHealth. “With such high expectations, there’s so much room for disappointment.” That was the case for Griffin, who has battled obesity since childhood and hoped to shed 70 pounds using Wegovy. The drug helped reduce her appetite and lowered her risk of diabetes, but she saw little change in weight. “It’s an emotional roller coaster,” she said. “You want it to work like it does for everybody else.” The medications are typically prescribed along with eating behavior and lifestyle changes. It’s usually clear within weeks whether someone will respond to the drugs, said Dr. Jody Dushay, an endocrine specialist at Beth Israel Deaconess Medical Center. Weight loss typically begins right away and continues as the dosage increases. For some patients, that just doesn't happen. For others, side effects such as nausea, vomiting and diarrhea force them to halt the medications, Dushay said. In such situations, patients who were counting on the new drugs to pare pounds may think they’re out of options. “I tell them: It's not game over,” Dushay said. Trying a different version of the new class of drugs may help. Griffin, who didn't respond well to Wegovy, has started using Zepbound, which targets an additional hormone pathway in the body. After three months of using the drug, she has lost 7 pounds. “I'm hoping it's slow and steady,” she said. Other people respond well to older drugs, the experts said. Changing diet, exercise, sleep and stress habits can also have profound effects. Figuring out what works typically requires a doctor trained to treat obesity, Saunders noted. “Obesity is such a complex disease that really needs to be treated very comprehensively,” she said. “If what we’re prescribing doesn’t work, we always have a backup plan.” The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Science and Educational Media Group. The AP is solely responsible for all content.WWE management seems to be slyly hinting that one of their most beloved and long-lasting stars may soon return to the ring. RAW General Manager Adam Pearce posted a cryptic image to Twitter/X ahead of this coming week's episode airing, showing AJ Styles caught mid-yell at Money in the Bank. pic.twitter.com/0vBfgQc377 In October, Styles made his long-awaited in-ring return to WWE during the Friday Night SmackDown leading up to Bad Blood. Introduced by country music star Hardy, Styles squared off against Carmelo Hayes, with the winner earning a future title shot against LA Knight for the WWE United States Championship. More News: Former WWE Champion's In-Ring Return Cut Short By Questionable Injury Unfortunately, the match took an unexpected turn. Midway through the bout, Styles appeared to suffer an ankle injury, prompting the referee to stop the match and declare Hayes the winner. WWE continued to update fans throughout the show, showing footage of Styles and providing details about his condition. Concern grew among fans, especially given that Styles had only just returned from a previous injury. Later, WWE personality Jackie Redmond confirmed on social media that Styles had sustained a mid-foot ligament sprain, more commonly known as a Lisfranc injury. "After last night's SmackDown, I can confirm that AJ Styles suffered a 'mid-foot ligament sprain,' also called a Lisfranc injury," Redmond tweeted. "AJ will undergo an MRI later this week to determine the severity of the injury." Styles himself would later confirm the injury via X/Twitter, saying, "It's called a Lisfranc injury. Look it up, it sucks! I thought when I took off my boot, I would have a bone sticking out of my foot." Styles is widely regarded as one of the best wrestlers of his generation, known for his high-flying, technical wrestling style. He began his career in the late 1990s, gaining fame in TNA (now Impact Wrestling), where he became a multi-time world champion and helped define the X-Division. His success continued in New Japan Pro Wrestling (NJPW), where he led the Bullet Club and won the IWGP Heavyweight Championship. More News: Former WWE Champion AJ Styles Gives Unfortunate Injury Update Styles joined officially WWE in 2016, capturing the WWE World Heavyweight Championship and becoming a three-time WWE Champion and former Universal Champion. If Styles is returning to the ring soon, it would be a huge boost for the company and thrilling for fans to see a living legend back in action. For more on WWE, head to Newsweek Sports .
Intoxicated man yells profanities at police from his apartment; drunk woman passes out on walking path: Berea police blotterJoin this golf club and you’ll get 7 ‘home’ courses across the US
How to Watch Top 25 Women’s College Basketball Games – Thursday, December 5
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